In vivo incorporation of14C-phenylalanine into ascidian tunichrome

X. He; K. Kustin; David Parry; W. E. Robinson; G. Ruberto; K. Nakanishi

doi:10.1007/BF01923431

In vivo incorporation of14C-phenylalanine into ascidian tunichrome

X. He, K. Kustin, David Parry, W. E. Robinson, G. Ruberto, K. Nakanishi

Research output: Contribution to journal › Comment/debate

Abstract

Ascidia ceratodes exposed to14C-phenylalanine in the surrounding seawater incorporates the radiolabel into newly biosynthesized tunichrome molecules. Radioactivity can be detected in tunichrome extracted from circulating blood cells within one day following initial exposure to the radiolabel; weak activity (≤4 μCi/mol tunichrome=22 nmol phenylalanine/mol tunichrome) is detected in 1 to 10 days; significantly higher amounts of radiolabel (57 μCi/mol tunichrome=318 nmol phenylalanine/mol tunichrome) appear 20 days after seawater exposure. Therefore, phenylalanine can function as a precursor in the biosynthesis of tunichrome.

Original language	English
Pages (from-to)	367-371
Number of pages	5
Journal	Experientia
Volume	48
Issue number	4
DOIs	https://doi.org/10.1007/BF01923431
Publication status	Published - 1992

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@article{b2ebc6d706e249a587dd824d341c5647,

title = "In vivo incorporation of14C-phenylalanine into ascidian tunichrome",

abstract = "Ascidia ceratodes exposed to14C-phenylalanine in the surrounding seawater incorporates the radiolabel into newly biosynthesized tunichrome molecules. Radioactivity can be detected in tunichrome extracted from circulating blood cells within one day following initial exposure to the radiolabel; weak activity (≤4 μCi/mol tunichrome=22 nmol phenylalanine/mol tunichrome) is detected in 1 to 10 days; significantly higher amounts of radiolabel (57 μCi/mol tunichrome=318 nmol phenylalanine/mol tunichrome) appear 20 days after seawater exposure. Therefore, phenylalanine can function as a precursor in the biosynthesis of tunichrome.",

keywords = "Ascidian, Blood pigments, Phenylalanine, Tunicates, Tunichrome",

author = "X. He and K. Kustin and David Parry and Robinson, {W. E.} and G. Ruberto and K. Nakanishi",

year = "1992",

doi = "10.1007/BF01923431",

language = "English",

volume = "48",

pages = "367--371",

journal = "Experientia",

issn = "0014-4754",

publisher = "Birkhauser Verlag Basel",

number = "4",

}

TY - JOUR

T1 - In vivo incorporation of14C-phenylalanine into ascidian tunichrome

AU - He, X.

AU - Kustin, K.

AU - Parry, David

AU - Robinson, W. E.

AU - Ruberto, G.

AU - Nakanishi, K.

PY - 1992

Y1 - 1992

N2 - Ascidia ceratodes exposed to14C-phenylalanine in the surrounding seawater incorporates the radiolabel into newly biosynthesized tunichrome molecules. Radioactivity can be detected in tunichrome extracted from circulating blood cells within one day following initial exposure to the radiolabel; weak activity (≤4 μCi/mol tunichrome=22 nmol phenylalanine/mol tunichrome) is detected in 1 to 10 days; significantly higher amounts of radiolabel (57 μCi/mol tunichrome=318 nmol phenylalanine/mol tunichrome) appear 20 days after seawater exposure. Therefore, phenylalanine can function as a precursor in the biosynthesis of tunichrome.

AB - Ascidia ceratodes exposed to14C-phenylalanine in the surrounding seawater incorporates the radiolabel into newly biosynthesized tunichrome molecules. Radioactivity can be detected in tunichrome extracted from circulating blood cells within one day following initial exposure to the radiolabel; weak activity (≤4 μCi/mol tunichrome=22 nmol phenylalanine/mol tunichrome) is detected in 1 to 10 days; significantly higher amounts of radiolabel (57 μCi/mol tunichrome=318 nmol phenylalanine/mol tunichrome) appear 20 days after seawater exposure. Therefore, phenylalanine can function as a precursor in the biosynthesis of tunichrome.

KW - Ascidian

KW - Blood pigments

KW - Phenylalanine

KW - Tunicates

KW - Tunichrome

U2 - 10.1007/BF01923431

DO - 10.1007/BF01923431

M3 - Comment/debate

SN - 0014-4754

VL - 48

SP - 367

EP - 371

JO - Experientia

JF - Experientia

IS - 4

ER -

In vivo incorporation of14C-phenylalanine into ascidian tunichrome

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