In vivo penicillin MIC drift to extremely high resistance in Serotype 14 Streptococcus pneumoniae persistently colonizing the nasopharynx of an infant with chronic suppurative lung disease: a case study

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    Abstract

    This is the first report of in vivo pneumococcal penicillin MIC drift from 4.0 to 16.0 mg/liter, possibly associated with alterations in the pbp1a gene. The case presented here is of an infant with early onset recurrent pneumonia and chronic bronchitis requiring repeated antibiotics
    Original languageEnglish
    Pages (from-to)3648-3649
    Number of pages2
    JournalAntimicrobial Agents and Chemotherapy
    Volume46
    Issue number11
    DOIs
    Publication statusPublished - 2002

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