Incident haemodialysis and outcomes in the Top End of Australia

Jaquelyne T. Hughes, Sandawana W. Majoni, Federica Barzi, Tegan M. Harris, Selina Signal, Gwendoline Lowah, Jola Kapojos, Asanga Abeyaratne, Madhivanan Sundaram, Paul Goldrick, Sarah L. Jones, Robert McFarlane, Lewis T. Campbell, Dianne Stephens, Alan Cass

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Objective: The Northern Territory has the highest incidence of haemodialysis care for end-stage kidney disease in Australia. Although acute kidney injury (AKI) is a recognised risk for chronic kidney disease (CKD), the effect of AKI causing incident haemodialysis ( i HD) is unknown. Audits identifying antecedents of i HD may inform health service planning. Thus, the aims of this study were to describe: (1) the development of an i HD recording system involving patients with AKI and CKD and (2) the incidence, patient characteristics and mortality for patients with dialysis-requiring AKI.

Methods: A retrospective data linkage study was conducted using eight clinical and administrative datasets of adults receiving i HD during the period from July 2011 to December 2012 within a major northern Australian hospital for AKI without CKD (AKI), AKI in people with pre-existing CKD (AKI/CKD) and CKD (without AKI). The time to death was identified by the Northern Territory Register of deaths.

Results: In all, 121 i HD treatments were provided for the cohort, whose mean age was 51.5 years with 53.7% female, 68.6% Aboriginal ethnicity and 46.3% with diabetes. i HD was provided for AKI (23.1%), AKI/CKD (47.1%) and CKD (29.8%). The 90-day mortality rate was 25.6% (AKI 39.3%, AKI/CKD 22.8%, CKD 19.4%). The 3-year mortality rate was 45.5% (AKI 53.6%, AKI/CKD 22.8%, CKD 19.4%). The time between requesting data from custodians and receipt of data ranged from 15 to 1046 days.

Conclusion: AKI in people with pre-existing CKD was a common cause of i HD. Health service planning and community health may benefit from AKI prevention strategies and the implementation of sustainable and permanent linkages with the datasets used to monitor prospective incident haemodialysis. What is known about the topic?: AKI is a risk factor for CKD. The Northern Territory has the highest national incidence rates of dialysis-dependent end-stage kidney disease, but has no audit tool describing outcomes of dialysis-requiring AKI. What does this paper add?: We audited all i HD and showed 25.6% mortality within the first 90 days of i HD and 45.5% overall mortality at 3 years. AKI in people with pre-existing CKD caused 47.1% of i HD. What are the implications for practitioners?: Health service planning and community health may benefit from AKI prevention strategies and the implementation of sustainable and permanent linkages with the datasets used to monitor prospective incident haemodialysis.

Original languageEnglish
Pages (from-to)A-G
Number of pages7
JournalAustralian Health Review
DOIs
Publication statusE-pub ahead of print - 18 Apr 2019

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Acute Kidney Injury
Renal Dialysis
Chronic Renal Insufficiency
Northern Territory
Health Planning
Mortality
Health Services
Dialysis
Insurance Benefits
Chronic Kidney Failure
Incidence
Information Storage and Retrieval

Cite this

Hughes, Jaquelyne T. ; Majoni, Sandawana W. ; Barzi, Federica ; Harris, Tegan M. ; Signal, Selina ; Lowah, Gwendoline ; Kapojos, Jola ; Abeyaratne, Asanga ; Sundaram, Madhivanan ; Goldrick, Paul ; Jones, Sarah L. ; McFarlane, Robert ; Campbell, Lewis T. ; Stephens, Dianne ; Cass, Alan. / Incident haemodialysis and outcomes in the Top End of Australia. In: Australian Health Review. 2019 ; pp. A-G.
@article{0118c1f806d4481cafbe62e2d2055295,
title = "Incident haemodialysis and outcomes in the Top End of Australia",
abstract = "Objective: The Northern Territory has the highest incidence of haemodialysis care for end-stage kidney disease in Australia. Although acute kidney injury (AKI) is a recognised risk for chronic kidney disease (CKD), the effect of AKI causing incident haemodialysis ( i HD) is unknown. Audits identifying antecedents of i HD may inform health service planning. Thus, the aims of this study were to describe: (1) the development of an i HD recording system involving patients with AKI and CKD and (2) the incidence, patient characteristics and mortality for patients with dialysis-requiring AKI. Methods: A retrospective data linkage study was conducted using eight clinical and administrative datasets of adults receiving i HD during the period from July 2011 to December 2012 within a major northern Australian hospital for AKI without CKD (AKI), AKI in people with pre-existing CKD (AKI/CKD) and CKD (without AKI). The time to death was identified by the Northern Territory Register of deaths. Results: In all, 121 i HD treatments were provided for the cohort, whose mean age was 51.5 years with 53.7{\%} female, 68.6{\%} Aboriginal ethnicity and 46.3{\%} with diabetes. i HD was provided for AKI (23.1{\%}), AKI/CKD (47.1{\%}) and CKD (29.8{\%}). The 90-day mortality rate was 25.6{\%} (AKI 39.3{\%}, AKI/CKD 22.8{\%}, CKD 19.4{\%}). The 3-year mortality rate was 45.5{\%} (AKI 53.6{\%}, AKI/CKD 22.8{\%}, CKD 19.4{\%}). The time between requesting data from custodians and receipt of data ranged from 15 to 1046 days. Conclusion: AKI in people with pre-existing CKD was a common cause of i HD. Health service planning and community health may benefit from AKI prevention strategies and the implementation of sustainable and permanent linkages with the datasets used to monitor prospective incident haemodialysis. What is known about the topic?: AKI is a risk factor for CKD. The Northern Territory has the highest national incidence rates of dialysis-dependent end-stage kidney disease, but has no audit tool describing outcomes of dialysis-requiring AKI. What does this paper add?: We audited all i HD and showed 25.6{\%} mortality within the first 90 days of i HD and 45.5{\%} overall mortality at 3 years. AKI in people with pre-existing CKD caused 47.1{\%} of i HD. What are the implications for practitioners?: Health service planning and community health may benefit from AKI prevention strategies and the implementation of sustainable and permanent linkages with the datasets used to monitor prospective incident haemodialysis.",
keywords = "acute kidney injury, end-stage kidney disease, health services, Indigenous Australian",
author = "Hughes, {Jaquelyne T.} and Majoni, {Sandawana W.} and Federica Barzi and Harris, {Tegan M.} and Selina Signal and Gwendoline Lowah and Jola Kapojos and Asanga Abeyaratne and Madhivanan Sundaram and Paul Goldrick and Jones, {Sarah L.} and Robert McFarlane and Campbell, {Lewis T.} and Dianne Stephens and Alan Cass",
year = "2019",
month = "4",
day = "18",
doi = "10.1071/AH18230",
language = "English",
pages = "A--G",
journal = "Australian Health Review",
issn = "1743-8462",
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Hughes, JT, Majoni, SW, Barzi, F, Harris, TM, Signal, S, Lowah, G, Kapojos, J, Abeyaratne, A, Sundaram, M, Goldrick, P, Jones, SL, McFarlane, R, Campbell, LT, Stephens, D & Cass, A 2019, 'Incident haemodialysis and outcomes in the Top End of Australia', Australian Health Review, pp. A-G. https://doi.org/10.1071/AH18230

Incident haemodialysis and outcomes in the Top End of Australia. / Hughes, Jaquelyne T.; Majoni, Sandawana W.; Barzi, Federica; Harris, Tegan M.; Signal, Selina; Lowah, Gwendoline; Kapojos, Jola; Abeyaratne, Asanga; Sundaram, Madhivanan; Goldrick, Paul; Jones, Sarah L.; McFarlane, Robert; Campbell, Lewis T.; Stephens, Dianne; Cass, Alan.

In: Australian Health Review, 18.04.2019, p. A-G.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Incident haemodialysis and outcomes in the Top End of Australia

AU - Hughes, Jaquelyne T.

AU - Majoni, Sandawana W.

AU - Barzi, Federica

AU - Harris, Tegan M.

AU - Signal, Selina

AU - Lowah, Gwendoline

AU - Kapojos, Jola

AU - Abeyaratne, Asanga

AU - Sundaram, Madhivanan

AU - Goldrick, Paul

AU - Jones, Sarah L.

AU - McFarlane, Robert

AU - Campbell, Lewis T.

AU - Stephens, Dianne

AU - Cass, Alan

PY - 2019/4/18

Y1 - 2019/4/18

N2 - Objective: The Northern Territory has the highest incidence of haemodialysis care for end-stage kidney disease in Australia. Although acute kidney injury (AKI) is a recognised risk for chronic kidney disease (CKD), the effect of AKI causing incident haemodialysis ( i HD) is unknown. Audits identifying antecedents of i HD may inform health service planning. Thus, the aims of this study were to describe: (1) the development of an i HD recording system involving patients with AKI and CKD and (2) the incidence, patient characteristics and mortality for patients with dialysis-requiring AKI. Methods: A retrospective data linkage study was conducted using eight clinical and administrative datasets of adults receiving i HD during the period from July 2011 to December 2012 within a major northern Australian hospital for AKI without CKD (AKI), AKI in people with pre-existing CKD (AKI/CKD) and CKD (without AKI). The time to death was identified by the Northern Territory Register of deaths. Results: In all, 121 i HD treatments were provided for the cohort, whose mean age was 51.5 years with 53.7% female, 68.6% Aboriginal ethnicity and 46.3% with diabetes. i HD was provided for AKI (23.1%), AKI/CKD (47.1%) and CKD (29.8%). The 90-day mortality rate was 25.6% (AKI 39.3%, AKI/CKD 22.8%, CKD 19.4%). The 3-year mortality rate was 45.5% (AKI 53.6%, AKI/CKD 22.8%, CKD 19.4%). The time between requesting data from custodians and receipt of data ranged from 15 to 1046 days. Conclusion: AKI in people with pre-existing CKD was a common cause of i HD. Health service planning and community health may benefit from AKI prevention strategies and the implementation of sustainable and permanent linkages with the datasets used to monitor prospective incident haemodialysis. What is known about the topic?: AKI is a risk factor for CKD. The Northern Territory has the highest national incidence rates of dialysis-dependent end-stage kidney disease, but has no audit tool describing outcomes of dialysis-requiring AKI. What does this paper add?: We audited all i HD and showed 25.6% mortality within the first 90 days of i HD and 45.5% overall mortality at 3 years. AKI in people with pre-existing CKD caused 47.1% of i HD. What are the implications for practitioners?: Health service planning and community health may benefit from AKI prevention strategies and the implementation of sustainable and permanent linkages with the datasets used to monitor prospective incident haemodialysis.

AB - Objective: The Northern Territory has the highest incidence of haemodialysis care for end-stage kidney disease in Australia. Although acute kidney injury (AKI) is a recognised risk for chronic kidney disease (CKD), the effect of AKI causing incident haemodialysis ( i HD) is unknown. Audits identifying antecedents of i HD may inform health service planning. Thus, the aims of this study were to describe: (1) the development of an i HD recording system involving patients with AKI and CKD and (2) the incidence, patient characteristics and mortality for patients with dialysis-requiring AKI. Methods: A retrospective data linkage study was conducted using eight clinical and administrative datasets of adults receiving i HD during the period from July 2011 to December 2012 within a major northern Australian hospital for AKI without CKD (AKI), AKI in people with pre-existing CKD (AKI/CKD) and CKD (without AKI). The time to death was identified by the Northern Territory Register of deaths. Results: In all, 121 i HD treatments were provided for the cohort, whose mean age was 51.5 years with 53.7% female, 68.6% Aboriginal ethnicity and 46.3% with diabetes. i HD was provided for AKI (23.1%), AKI/CKD (47.1%) and CKD (29.8%). The 90-day mortality rate was 25.6% (AKI 39.3%, AKI/CKD 22.8%, CKD 19.4%). The 3-year mortality rate was 45.5% (AKI 53.6%, AKI/CKD 22.8%, CKD 19.4%). The time between requesting data from custodians and receipt of data ranged from 15 to 1046 days. Conclusion: AKI in people with pre-existing CKD was a common cause of i HD. Health service planning and community health may benefit from AKI prevention strategies and the implementation of sustainable and permanent linkages with the datasets used to monitor prospective incident haemodialysis. What is known about the topic?: AKI is a risk factor for CKD. The Northern Territory has the highest national incidence rates of dialysis-dependent end-stage kidney disease, but has no audit tool describing outcomes of dialysis-requiring AKI. What does this paper add?: We audited all i HD and showed 25.6% mortality within the first 90 days of i HD and 45.5% overall mortality at 3 years. AKI in people with pre-existing CKD caused 47.1% of i HD. What are the implications for practitioners?: Health service planning and community health may benefit from AKI prevention strategies and the implementation of sustainable and permanent linkages with the datasets used to monitor prospective incident haemodialysis.

KW - acute kidney injury

KW - end-stage kidney disease

KW - health services

KW - Indigenous Australian

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