Interrupter Respiratory Resistance in Healthy Chinese Preschool Children

A Li, H LAM, H SO, M LEUNG, T TSEN, C AU, Anne Chang

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    Background: Interrupter respiratory resistance (Rint) is useful in evaluating lung function in children who cannot perform the traditional lung function tests. However, available reference Rint values are confined to whites. Our aims were as follows: (1) to establish reference values in local preschool Chinese children, (2) to examine their relationship with demographic and anthropometric factors, and (3) to determine the 10-min and 6-week repeatability of Rint. Methods: Rint was measured in preschool children from randomly chosen local kindergartens, and the repeatability of Rint measurement was assessed in a subgroup of subjects 10 min and 6 weeks after the initial measurement. Results: Rint measurement was performed in 509 children between 4 and 6 years of age. Age, height, and weight significantly inversely correlated with Rint values. However, on multiple linear regression, height was the only variable that independently correlated with Rint. Repeat measurements obtained 10 min and 6 weeks after the initial reading in 45 children showed good agreement with little variability, and the interclass correlation coefficients for 10-min and 6-week measurements were 0.877 and 0.923, respectively. Conclusion: Rint reference centile curves for Chinese preschool children have been determined. Rint in preschool Chinese children has good short- and long-term repeatability. � 2009 American College of Chest Physicians.
    Original languageEnglish
    Pages (from-to)554-560
    Number of pages7
    JournalChest
    Volume136
    Issue number2
    Publication statusPublished - 2009

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    Preschool Children
    Reference Values
    Respiratory Function Tests
    Reading
    Linear Models
    Demography
    Weights and Measures
    Lung

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    Li, A., LAM, H., SO, H., LEUNG, M., TSEN, T., AU, C., & Chang, A. (2009). Interrupter Respiratory Resistance in Healthy Chinese Preschool Children. Chest, 136(2), 554-560.
    Li, A ; LAM, H ; SO, H ; LEUNG, M ; TSEN, T ; AU, C ; Chang, Anne. / Interrupter Respiratory Resistance in Healthy Chinese Preschool Children. In: Chest. 2009 ; Vol. 136, No. 2. pp. 554-560.
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    title = "Interrupter Respiratory Resistance in Healthy Chinese Preschool Children",
    abstract = "Background: Interrupter respiratory resistance (Rint) is useful in evaluating lung function in children who cannot perform the traditional lung function tests. However, available reference Rint values are confined to whites. Our aims were as follows: (1) to establish reference values in local preschool Chinese children, (2) to examine their relationship with demographic and anthropometric factors, and (3) to determine the 10-min and 6-week repeatability of Rint. Methods: Rint was measured in preschool children from randomly chosen local kindergartens, and the repeatability of Rint measurement was assessed in a subgroup of subjects 10 min and 6 weeks after the initial measurement. Results: Rint measurement was performed in 509 children between 4 and 6 years of age. Age, height, and weight significantly inversely correlated with Rint values. However, on multiple linear regression, height was the only variable that independently correlated with Rint. Repeat measurements obtained 10 min and 6 weeks after the initial reading in 45 children showed good agreement with little variability, and the interclass correlation coefficients for 10-min and 6-week measurements were 0.877 and 0.923, respectively. Conclusion: Rint reference centile curves for Chinese preschool children have been determined. Rint in preschool Chinese children has good short- and long-term repeatability. � 2009 American College of Chest Physicians.",
    keywords = "age determination, anthropometry, article, body height, body weight, child, Chinese, demography, female, human, human experiment, interrupter respiratory resistance, lung function test, male, normal human, preschool child, priority journal, reference value, Age Factors, Airway Resistance, Anthropometry, Child, Child Welfare, Child, Preschool, China, Cohort Studies, Female, Humans, Linear Models, Male, Mass Screening, Probability, Reference Values, Respiratory Function Tests, Respiratory System, Sex Factors, Statistics, Nonparametric",
    author = "A Li and H LAM and H SO and M LEUNG and T TSEN and C AU and Anne Chang",
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    Li, A, LAM, H, SO, H, LEUNG, M, TSEN, T, AU, C & Chang, A 2009, 'Interrupter Respiratory Resistance in Healthy Chinese Preschool Children', Chest, vol. 136, no. 2, pp. 554-560.

    Interrupter Respiratory Resistance in Healthy Chinese Preschool Children. / Li, A; LAM, H; SO, H; LEUNG, M; TSEN, T; AU, C; Chang, Anne.

    In: Chest, Vol. 136, No. 2, 2009, p. 554-560.

    Research output: Contribution to journalArticleResearchpeer-review

    TY - JOUR

    T1 - Interrupter Respiratory Resistance in Healthy Chinese Preschool Children

    AU - Li, A

    AU - LAM, H

    AU - SO, H

    AU - LEUNG, M

    AU - TSEN, T

    AU - AU, C

    AU - Chang, Anne

    PY - 2009

    Y1 - 2009

    N2 - Background: Interrupter respiratory resistance (Rint) is useful in evaluating lung function in children who cannot perform the traditional lung function tests. However, available reference Rint values are confined to whites. Our aims were as follows: (1) to establish reference values in local preschool Chinese children, (2) to examine their relationship with demographic and anthropometric factors, and (3) to determine the 10-min and 6-week repeatability of Rint. Methods: Rint was measured in preschool children from randomly chosen local kindergartens, and the repeatability of Rint measurement was assessed in a subgroup of subjects 10 min and 6 weeks after the initial measurement. Results: Rint measurement was performed in 509 children between 4 and 6 years of age. Age, height, and weight significantly inversely correlated with Rint values. However, on multiple linear regression, height was the only variable that independently correlated with Rint. Repeat measurements obtained 10 min and 6 weeks after the initial reading in 45 children showed good agreement with little variability, and the interclass correlation coefficients for 10-min and 6-week measurements were 0.877 and 0.923, respectively. Conclusion: Rint reference centile curves for Chinese preschool children have been determined. Rint in preschool Chinese children has good short- and long-term repeatability. � 2009 American College of Chest Physicians.

    AB - Background: Interrupter respiratory resistance (Rint) is useful in evaluating lung function in children who cannot perform the traditional lung function tests. However, available reference Rint values are confined to whites. Our aims were as follows: (1) to establish reference values in local preschool Chinese children, (2) to examine their relationship with demographic and anthropometric factors, and (3) to determine the 10-min and 6-week repeatability of Rint. Methods: Rint was measured in preschool children from randomly chosen local kindergartens, and the repeatability of Rint measurement was assessed in a subgroup of subjects 10 min and 6 weeks after the initial measurement. Results: Rint measurement was performed in 509 children between 4 and 6 years of age. Age, height, and weight significantly inversely correlated with Rint values. However, on multiple linear regression, height was the only variable that independently correlated with Rint. Repeat measurements obtained 10 min and 6 weeks after the initial reading in 45 children showed good agreement with little variability, and the interclass correlation coefficients for 10-min and 6-week measurements were 0.877 and 0.923, respectively. Conclusion: Rint reference centile curves for Chinese preschool children have been determined. Rint in preschool Chinese children has good short- and long-term repeatability. � 2009 American College of Chest Physicians.

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    Li A, LAM H, SO H, LEUNG M, TSEN T, AU C et al. Interrupter Respiratory Resistance in Healthy Chinese Preschool Children. Chest. 2009;136(2):554-560.