TY - JOUR
T1 - Investigating Crimean-Congo haemorrhagic fever virus seropositivity in camels and human behavioural risks in an abattoir in Nigeria
AU - Adamu, Andrew Musa
AU - Onoja, Anyebe Bernard
AU - Ugbodu, Victoria Ehinor
AU - Bala, Reuben Sylvester
AU - Maina, Meshach
AU - Salisu, Usman Shehu
AU - Pewan, Shedrach Benjamin
AU - David, Emmanuel
AU - Malgwi, Arhyel
AU - Adamu, Cornelius
AU - Adeiza, Abdulrahman
AU - Herbert, Megan
AU - Horwood, Paul
AU - Adegboye, Oyelola
N1 - Publisher Copyright:
© The Author(s), 2024. Published by Cambridge University Press.
PY - 2024/2/1
Y1 - 2024/2/1
N2 - Crimean-Congo haemorrhagic fever virus (CCHFV) is an emerging viral pathogen with pandemic potential that is often misdiagnosed. Case fatality in low-resource settings could be up to 40% due to close contact between animals and humans. A two-year cross-sectional study was conducted in Fagge abattoir, Kano State, Nigeria, to estimate the seropositivity of CCHFV in camels using a commercial multi-species competitive enzyme-linked immunosorbent assay (ELISA). A closed-ended questionnaire was administered to the abattoir workers to assess their awareness, mitigation, and behavioural practices associated with CCHF. Of the 184 camels tested, 179 (97%) were seropositive for CCHFV (95% confidence interval (CI): 93.77, 99.11). The median (interquartile range (IQR)) age of respondents was 41 (35-52), with 62% having no education. Respondents had little knowledge about CCHFV and the concept of zoonotic disease. In this study, the high estimated prevalence of antibodies to CCHFV in camels highlights the heightened risk of transmission of CCHFV in Nigeria. Similarly, a concerning lack of knowledge and inadequate preventive practices, alongside a prevalence of high-risk behaviours associated with CCHF among abattoir workers, were noted in this study. Thus, there is an urgent need for comprehensive public health education and collaborative One Health strategies to avert the threats of spillover events.
AB - Crimean-Congo haemorrhagic fever virus (CCHFV) is an emerging viral pathogen with pandemic potential that is often misdiagnosed. Case fatality in low-resource settings could be up to 40% due to close contact between animals and humans. A two-year cross-sectional study was conducted in Fagge abattoir, Kano State, Nigeria, to estimate the seropositivity of CCHFV in camels using a commercial multi-species competitive enzyme-linked immunosorbent assay (ELISA). A closed-ended questionnaire was administered to the abattoir workers to assess their awareness, mitigation, and behavioural practices associated with CCHF. Of the 184 camels tested, 179 (97%) were seropositive for CCHFV (95% confidence interval (CI): 93.77, 99.11). The median (interquartile range (IQR)) age of respondents was 41 (35-52), with 62% having no education. Respondents had little knowledge about CCHFV and the concept of zoonotic disease. In this study, the high estimated prevalence of antibodies to CCHFV in camels highlights the heightened risk of transmission of CCHFV in Nigeria. Similarly, a concerning lack of knowledge and inadequate preventive practices, alongside a prevalence of high-risk behaviours associated with CCHF among abattoir workers, were noted in this study. Thus, there is an urgent need for comprehensive public health education and collaborative One Health strategies to avert the threats of spillover events.
KW - behavioural risks
KW - camels
KW - CCHFV
KW - mass gatherings
KW - Nigeria
KW - serology
UR - http://www.scopus.com/inward/record.url?scp=85184563562&partnerID=8YFLogxK
U2 - 10.1017/S0950268824000189
DO - 10.1017/S0950268824000189
M3 - Article
C2 - 38299329
AN - SCOPUS:85184563562
SN - 0950-2688
VL - 152
SP - 1
EP - 8
JO - Epidemiology and Infection
JF - Epidemiology and Infection
M1 - e29
ER -