TY - JOUR
T1 - Plasmodium vivax in the Era of the Shrinking P. falciparum Map
AU - Price, Ric N.
AU - Commons, Robert J.
AU - Battle, Katherine E.
AU - Thriemer, Kamala
AU - Mendis, Kamini
PY - 2020/6
Y1 - 2020/6
N2 - Plasmodium vivax is an important cause of malaria, associated with a significant public health burden. Whilst enhanced malaria-control activities have successfully reduced the incidence of Plasmodium falciparum malaria in many areas, there has been a consistent increase in the proportion of malaria due to P. vivax in regions where both parasites coexist. This article reviews the epidemiology and biology of P. vivax, how the parasite differs from P. falciparum, and the key features that render it more difficult to control and eliminate. Since transmission of the parasite is driven largely by relapses from dormant liver stages, its timely elimination will require widespread access to safe and effective radical cure.
AB - Plasmodium vivax is an important cause of malaria, associated with a significant public health burden. Whilst enhanced malaria-control activities have successfully reduced the incidence of Plasmodium falciparum malaria in many areas, there has been a consistent increase in the proportion of malaria due to P. vivax in regions where both parasites coexist. This article reviews the epidemiology and biology of P. vivax, how the parasite differs from P. falciparum, and the key features that render it more difficult to control and eliminate. Since transmission of the parasite is driven largely by relapses from dormant liver stages, its timely elimination will require widespread access to safe and effective radical cure.
KW - epidemiology
KW - Plasmodium falciparum
KW - Plasmodium vivax
KW - primaquine
UR - http://www.scopus.com/inward/record.url?scp=85083561625&partnerID=8YFLogxK
U2 - 10.1016/j.pt.2020.03.009
DO - 10.1016/j.pt.2020.03.009
M3 - Review article
C2 - 32407682
AN - SCOPUS:85083561625
SN - 1471-4922
VL - 36
SP - 560
EP - 570
JO - Trends in Parasitology
JF - Trends in Parasitology
IS - 6
ER -