Plasmodium vivax in the Era of the Shrinking P. falciparum Map

Ric N. Price, Robert J. Commons, Katherine E. Battle, Kamala Thriemer, Kamini Mendis

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Abstract

Plasmodium vivax is an important cause of malaria, associated with a significant public health burden. Whilst enhanced malaria-control activities have successfully reduced the incidence of Plasmodium falciparum malaria in many areas, there has been a consistent increase in the proportion of malaria due to P. vivax in regions where both parasites coexist. This article reviews the epidemiology and biology of P. vivax, how the parasite differs from P. falciparum, and the key features that render it more difficult to control and eliminate. Since transmission of the parasite is driven largely by relapses from dormant liver stages, its timely elimination will require widespread access to safe and effective radical cure.

Original languageEnglish
Pages (from-to)560-570
Number of pages11
JournalTrends in Parasitology
Volume36
Issue number6
Early online date22 Apr 2020
DOIs
Publication statusPublished - Jun 2020

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