TY - JOUR
T1 - Letter to the editor “Prognostic value of microRNAs in colorectal cancer: a meta-analysis”
AU - Jayaraj, Rama
AU - Kumarasamy, Chellan
AU - Muthukaliannan, Gothandam K
PY - 2018/9/13
Y1 - 2018/9/13
N2 - The systematic review and meta-analyses published by Gao et al1 regarding the topic of microRNAs as prognostic markers in colorectal cancer (CRC) has been of great interest to us. Although previous systematic reviews and meta-analyses highlighting the prognostic value of miRNAs as prognostic markers in CRC exist, each of those studies is primarily focused on a single miRNA per study.2,3 Gao et al,1 via this expansive study, have managed to assess and highlight the prognostic utility of a variety of miRNAs in CRC. Both miR-21 and miR-181 have been highlighted in previous studies as being potential prognostic markers, but interestingly, Gao et al’s1 study is the first to highlight miR-224 and miR-141 as strong prognostic biomarkers, specifically in CRC.
AB - The systematic review and meta-analyses published by Gao et al1 regarding the topic of microRNAs as prognostic markers in colorectal cancer (CRC) has been of great interest to us. Although previous systematic reviews and meta-analyses highlighting the prognostic value of miRNAs as prognostic markers in CRC exist, each of those studies is primarily focused on a single miRNA per study.2,3 Gao et al,1 via this expansive study, have managed to assess and highlight the prognostic utility of a variety of miRNAs in CRC. Both miR-21 and miR-181 have been highlighted in previous studies as being potential prognostic markers, but interestingly, Gao et al’s1 study is the first to highlight miR-224 and miR-141 as strong prognostic biomarkers, specifically in CRC.
UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145637/
UR - http://www.scopus.com/inward/record.url?scp=85057603128&partnerID=8YFLogxK
U2 - 10.2147/CMAR.S177875
DO - 10.2147/CMAR.S177875
M3 - Letter
C2 - 30271198
SN - 1179-1322
VL - 2018
SP - 3501
EP - 3503
JO - Cancer Management and Research
JF - Cancer Management and Research
IS - 10
ER -