Ee Min Christopher Toh, Parker Magin, Andrew Davey, Joshua Davis

Research output: Contribution to journalLetterpeer-review


I WAS READING with great interest the article by Magin et al published in Australian Journal of General Practice in January–February 2022, titled ‘Evidence-based strategies for better antibiotic prescribing’.1 I wanted to clarify a minor point. In the article the authors briefly mentioned a randomised controlled trial (RCT) conducted in Pakistan comparing amoxicillin versus placebo for mild-to-moderate pneumonia,2 stating that: ‘a recent RCT of antibiotics versus placebo in children with mild-to-moderate pneumonia in Pakistan showed that placebo was non-inferior to antibiotics’.1 However, when I referred to the published results of the trial, it was actually the opposite. The primary outcome of treatment failure at day 3 was 4.9% for placebo and 2.6% for amoxicillin, a difference of 2.3% (95% confidence interval [CI]: 0.9, 3.7) higher in the placebo group.2

Original languageEnglish
Pages (from-to)9
Number of pages1
JournalAustralian journal of general practice
Issue number1-2
Publication statusPublished - 2023


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