Management of melioidosis osteomyelitis and septic arthritis

R. P. Shetty, M Mathew, J Smith, L MORSE, M Mehta, Bart Currie

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    Little information is available about several important aspects of the treatment of melioidosis osteomyelitis and septic arthritis.

    We undertook a retrospective review of 50 patients with these conditions in an attempt to determine the effect of location of the disease, type of surgical intervention and duration of antibiotic treatment on outcome, particularly complications and relapse.

    We found that there was a 27.5% risk of osteomyelitis of the adjacent bone in patients with septic arthritis in the lower limb. Patients with septic arthritis and osteomyelitis of an adjacent bone were in hospital significantly longer (p = 0.001), needed more operations (p = 0.031) and had a significantly higher rate of complications and re-presentation (p = 0.048).

    More than half the patients (61%), most particularly those with multifocal bone and joint involvement, and those with septic arthritis and osteomyelitis of an adjacent bone who were treated operatively, needed more visits to theatre.
    Original languageEnglish
    Pages (from-to)277-282
    Number of pages6
    JournalBone and Joint Journal
    Volume97-B
    Issue number2
    DOIs
    Publication statusPublished - 2015

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    Melioidosis
    Infectious Arthritis
    Osteomyelitis
    Bone and Bones
    Lower Extremity
    Joints
    Anti-Bacterial Agents
    Recurrence

    Cite this

    Shetty, R. P. ; Mathew, M ; Smith, J ; MORSE, L ; Mehta, M ; Currie, Bart. / Management of melioidosis osteomyelitis and septic arthritis. In: Bone and Joint Journal. 2015 ; Vol. 97-B, No. 2. pp. 277-282.
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    abstract = "Little information is available about several important aspects of the treatment of melioidosis osteomyelitis and septic arthritis.We undertook a retrospective review of 50 patients with these conditions in an attempt to determine the effect of location of the disease, type of surgical intervention and duration of antibiotic treatment on outcome, particularly complications and relapse.We found that there was a 27.5{\%} risk of osteomyelitis of the adjacent bone in patients with septic arthritis in the lower limb. Patients with septic arthritis and osteomyelitis of an adjacent bone were in hospital significantly longer (p = 0.001), needed more operations (p = 0.031) and had a significantly higher rate of complications and re-presentation (p = 0.048).More than half the patients (61{\%}), most particularly those with multifocal bone and joint involvement, and those with septic arthritis and osteomyelitis of an adjacent bone who were treated operatively, needed more visits to theatre.",
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    Shetty, RP, Mathew, M, Smith, J, MORSE, L, Mehta, M & Currie, B 2015, 'Management of melioidosis osteomyelitis and septic arthritis', Bone and Joint Journal, vol. 97-B, no. 2, pp. 277-282. https://doi.org/10.1302/0301-620X.97B2.34799

    Management of melioidosis osteomyelitis and septic arthritis. / Shetty, R. P.; Mathew, M; Smith, J; MORSE, L; Mehta, M; Currie, Bart.

    In: Bone and Joint Journal, Vol. 97-B, No. 2, 2015, p. 277-282.

    Research output: Contribution to journalArticleResearchpeer-review

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