Mapping of incompatibility assay: Bringing method to problem in critical care

Suci Hanifah, Patrick Ball, Ross A Kennedy, Krishna Lambert

    Research output: Contribution to journalArticle

    Abstract

    Objective: This study aims to identify the methodology of incompatibility assay. This review is intended to inform further research into the management of these issues in a clinical setting in Indonesia.

    Methods:
     A search was conducted of incompatibility studies through International Pharmaceutical Abstract (IPA) using the keywords ‘compatibility’ OR ’incompatibility” AND ‘intravenous”, “parenteral” OR “infusion”.

    Results: 
    There are only two authors use in vivo setting and higher number of authors use in vitro setting. Among those who bring in vitro assays most of them use static approach between two drug combination.

    Conclusion
    : A standardized procedure is meaningful for general judgement for incompatibility. However, particularly in critical care, setting up an evaluation procedure that mimics as closely as possible real practice within the clinical area should be undertaken to validate practice.
    Original languageEnglish
    Pages (from-to)171-173
    Number of pages3
    JournalInternational Journal of Pharmacy and Pharmaceutical Sciences
    Volume6
    Issue number4
    Publication statusPublished - May 2014

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