In this research, the mechanical properties of various glass fibre reinforced polymer (GFRP) pultruded profiles exposed to seawater sea sand concrete (SWSSC) and its combination with UV radiation and water vapour condensation were studied. The effect of different conditions, duration of conditioning, and the profile cross-section configuration on the mechanical properties were investigated. Three-point bending, tension, and compression tests were carried out to obtain the mechanical properties, including flexural, tensile and compressive strengths and tensile elastic modulus. Furthermore, in order to scrutiny the mechanisms and extent of damage, scanning electron microscopy (SEM) was carried out on the test samples before and after the exposures. Finally, regression models were derived according to the experimental data to describe the mechanical properties of profiles after exposure to the aggressive environments used in this study. The maximum reductions of about 30%, 33% and 46% were observed in three-point bending, tensile and compressive tests, respectively amongst all samples when exposed for 90 days to simulated SWSSC. These reductions increased for the same sections to 52%, 47%, and 50% when the GFRP profiles were pre-exposed for 3000 h to UV radiation and moisture before exposing for 90 days to simulated SWSSC.