Mediastinitis

Could your case be a candidate for candida?

Bernadette Johnson, Joshua Davis, Maria Sisneros

Research output: Contribution to journalComment/debateResearch

Abstract

Background: Candida mediastinitis is rare, but mortality has been reported as high as 50%. There are no clinical trials evaluating treatment of Candida mediastinitis and there are only a limited number of reports in the literature. Case Report: We present two cases of mediastinitis after coronary artery bypass grafting due to Candida albicans. Immunosuppression and long surgical procedures were likely risk factors for the infections. After multiple hospitalizations and debridements there was concern for the development of resistance. However, the isolates were determined to be fluconazole-susceptible and the patients were treated with long-term oral fluconazole.
Conclusions: Candida mediastinitis is difficult to treat. Even with appropriate treatment, patients may require numerous surgical debridements.
Original languageEnglish
Pages (from-to)86-88
Number of pages3
JournalAmerican Journal of Case Reports
Volume13
DOIs
Publication statusPublished - 2012
Externally publishedYes

Fingerprint

Mediastinitis
Candida
Fluconazole
Debridement
Candida albicans
Coronary Artery Bypass
Immunosuppression
Hospitalization
Clinical Trials
Mortality
Therapeutics
Infection

Cite this

Johnson, Bernadette ; Davis, Joshua ; Sisneros, Maria. / Mediastinitis : Could your case be a candidate for candida?. In: American Journal of Case Reports. 2012 ; Vol. 13. pp. 86-88.
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Mediastinitis : Could your case be a candidate for candida? / Johnson, Bernadette; Davis, Joshua; Sisneros, Maria.

In: American Journal of Case Reports, Vol. 13, 2012, p. 86-88.

Research output: Contribution to journalComment/debateResearch

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AU - Sisneros, Maria

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