Abstract
| Original language | English |
|---|---|
| Title of host publication | Global Burden and Challenges of Melioidosis |
| Editors | Direk Limmathurotsakul, David Dance |
| Publisher | Multidisciplinary Digital Publishing Institute (MDPI) |
| Pages | 13-23 |
| Number of pages | 11 |
| ISBN (Electronic) | 978-3-03897-743-8 |
| ISBN (Print) | 978-3-03897-742-1 |
| DOIs | |
| Publication status | Published - Mar 2019 |
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Melioidosis : An Australian Perspective. / Smith, Simon; Hanson, Joshua; Currie, Bart.
Global Burden and Challenges of Melioidosis. ed. / Direk Limmathurotsakul; David Dance. Multidisciplinary Digital Publishing Institute (MDPI), 2019. p. 13-23.Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review
TY - CHAP
T1 - Melioidosis
T2 - An Australian Perspective
AU - Smith, Simon
AU - Hanson, Joshua
AU - Currie, Bart
N1 - This book is a printed edition of the Special Issue Global Burden and Challenges of Melioidosis that was published in TropicalMed.
PY - 2019/3
Y1 - 2019/3
N2 - Burkholderia pseudomallei is endemic in northern Australia, with cases of melioidosis most commonly occurring during the wet season in individuals with diabetes, hazardous alcohol use, and chronic kidney disease. Pneumonia is the most common presentation and the majority of patients are bacteraemic -however, infection may involve almost any organ, with the skin and soft tissues, genitourinary system, visceral organs, and bone and joints affected most commonly. Central nervous system involvement is rarer, but has a high attributable mortality. Increased awareness of the disease amongst healthcare providers, ready access to appropriate antibiotic therapy and high-quality intensive care services has resulted in a sharp decline in the case fatality rate over the last 20 years. Further improvement in clinical outcomes will require a greater understanding of the disease's pathophysiology, its optimal management, and more effective strategies for its prevention.
AB - Burkholderia pseudomallei is endemic in northern Australia, with cases of melioidosis most commonly occurring during the wet season in individuals with diabetes, hazardous alcohol use, and chronic kidney disease. Pneumonia is the most common presentation and the majority of patients are bacteraemic -however, infection may involve almost any organ, with the skin and soft tissues, genitourinary system, visceral organs, and bone and joints affected most commonly. Central nervous system involvement is rarer, but has a high attributable mortality. Increased awareness of the disease amongst healthcare providers, ready access to appropriate antibiotic therapy and high-quality intensive care services has resulted in a sharp decline in the case fatality rate over the last 20 years. Further improvement in clinical outcomes will require a greater understanding of the disease's pathophysiology, its optimal management, and more effective strategies for its prevention.
U2 - 10.3390/books978-3-03897-743-8
DO - 10.3390/books978-3-03897-743-8
M3 - Chapter
SN - 978-3-03897-742-1
SP - 13
EP - 23
BT - Global Burden and Challenges of Melioidosis
A2 - Limmathurotsakul, Direk
A2 - Dance, David
PB - Multidisciplinary Digital Publishing Institute (MDPI)
ER -