Melioidosis in New Caledonia: A dominant strain in a transmission hotspot

B. Melot; J. Colot; F. Lacassin; S. Tardieu; E. Lapisardi; M. Mayo; E. P. Price; D. S. Sarovich; B. J. Currie; C. Goarant

doi:10.1017/S0950268815002770

Melioidosis in New Caledonia: A dominant strain in a transmission hotspot

B. Melot, J. Colot, F. Lacassin, S. Tardieu, E. Lapisardi, M. Mayo, E. P. Price, D. S. Sarovich, B. J. Currie, C. Goarant

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3 Citations (Scopus)

Abstract

Melioidosis is an infectious disease caused by Burkholderia pseudomallei, a bacterium endemic in Southeast Asia and northern Australia. In New Caledonia, sporadic cases were first described in 2005; since then, more cases have been identified. To improve our understanding of melioidosis epidemiology in New Caledonia, we compared the local cases and B. pseudomallei isolates with those from endemic areas. Nineteen melioidosis cases have been diagnosed in New Caledonia since 1999, mostly severe and with frequent bacteraemia, leading to three (16%) fatalities. All but one occurred in the North Province. Besides sporadic cases caused by non-clonal strains, we also identified a hotspot of transmission related to a clonal group of B. pseudomallei that is phylogenetically related to Australian strains.

Original language	English
Pages (from-to)	1330-1337
Number of pages	8
Journal	Epidemiology and Infection
Volume	144
Issue number	6
DOIs	https://doi.org/10.1017/S0950268815002770 https://doi.org/10.1017/S0950268815002770
Publication status	Published - 1 Apr 2016

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© Copyright Cambridge University Press 2015.

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title = "Melioidosis in New Caledonia: A dominant strain in a transmission hotspot",

abstract = "Melioidosis is an infectious disease caused by Burkholderia pseudomallei, a bacterium endemic in Southeast Asia and northern Australia. In New Caledonia, sporadic cases were first described in 2005; since then, more cases have been identified. To improve our understanding of melioidosis epidemiology in New Caledonia, we compared the local cases and B. pseudomallei isolates with those from endemic areas. Nineteen melioidosis cases have been diagnosed in New Caledonia since 1999, mostly severe and with frequent bacteraemia, leading to three (16%) fatalities. All but one occurred in the North Province. Besides sporadic cases caused by non-clonal strains, we also identified a hotspot of transmission related to a clonal group of B. pseudomallei that is phylogenetically related to Australian strains.",

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T2 - A dominant strain in a transmission hotspot

AU - Melot, B.

AU - Colot, J.

AU - Lacassin, F.

AU - Tardieu, S.

AU - Lapisardi, E.

AU - Mayo, M.

AU - Price, E. P.

AU - Sarovich, D. S.

AU - Currie, B. J.

AU - Goarant, C.

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AB - Melioidosis is an infectious disease caused by Burkholderia pseudomallei, a bacterium endemic in Southeast Asia and northern Australia. In New Caledonia, sporadic cases were first described in 2005; since then, more cases have been identified. To improve our understanding of melioidosis epidemiology in New Caledonia, we compared the local cases and B. pseudomallei isolates with those from endemic areas. Nineteen melioidosis cases have been diagnosed in New Caledonia since 1999, mostly severe and with frequent bacteraemia, leading to three (16%) fatalities. All but one occurred in the North Province. Besides sporadic cases caused by non-clonal strains, we also identified a hotspot of transmission related to a clonal group of B. pseudomallei that is phylogenetically related to Australian strains.

KW - Epidemiology

KW - melioidosis

KW - molecular epidemiology

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SP - 1330

EP - 1337

JO - Epidemiology and Infection

JF - Epidemiology and Infection

IS - 6

ER -

Melioidosis in New Caledonia: A dominant strain in a transmission hotspot

Abstract

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