@article{b9f9d581519848af92e967df8c19cc7a,
title = "Microevolution of Burkholderia pseudomallei during an acute infection",
abstract = "We used whole-genome sequencing to evaluate 69 independent colonies of Burkholderia pseudomallei isolated from seven body sites of a patient with acute disseminated melioidosis. Fourteen closely related genotypes were found, providing evidence for the rapid in vivo diversification of B. pseudomallei after inoculation and systemic spread. ",
keywords = "bacterial DNA, bacterial genome, Burkholderia pseudomallei, case report, chemistry, classification, DNA sequence, genetic variability, genetics, genotype, human, isolation and purification, male, melioidosis, microbiology, molecular evolution, molecular genetics, young adult, DNA, Bacterial, Evolution, Molecular, Genetic Variation, Genome, Bacterial, Genotype, Humans, Male, Melioidosis, Molecular Sequence Data, Sequence Analysis, DNA, Young Adult",
author = "Direk Limmathurotsakul and Matthew Holden and Paul Coupland and Erin Price and Narisara Chantratitia and Vanaporn Wuthiekanun and Premjit Amornchai and Julian Parkhill and Peacock, {Sharon J}",
year = "2014",
doi = "10.1128/JCM.01219-14",
language = "English",
volume = "52",
pages = "3418--3421",
journal = "Journal of Clinical Microbiology",
issn = "0095-1137",
publisher = "American Society for Microbiology",
number = "9",
}