Abstract
Background: Gestational diabetes mellitus (GDM) is defined as glucose intolerance with its onset or first recognition during pregnancy. Post-GDM women have a life-time risk exceeding 70% of developing type 2 diabetes mellitus (T2DM). Lifestyle modifications reduce the incidence of T2DM by up to 58% for high-risk individuals.
Methods/Design: The Mothers After Gestational Diabetes in Australia Diabetes
Prevention Program (MAGDA-DPP) is a randomized controlled trial aiming to
assess the effectiveness of a structured diabetes prevention intervention for
post-GDM women. This trial has an intervention group participating in a
diabetes prevention program (DPP), and a control group receiving usual care
from their general practitioners during the same time period. The 12-month
intervention comprises an individual session followed by five group sessions at
two-week intervals, and two follow-up telephone calls. A total of 574 women
will be recruited, with 287 in each arm. The women will undergo blood tests, anthropometric
measurements, and self-reported health status, diet, physical activity, quality
of life, depression, risk perception and healthcare service usage, at baseline
and 12 months. At completion, primary outcome (changes in diabetes risk) and
secondary outcome (changes in psychosocial and quality of life measurements and
in cardiovascular disease risk factors) will be assessed in both groups.
Discussion: This study aims to show whether MAGDA-DPP leads to a
reduction in diabetes risk for post-GDM women. The characteristics that predict
intervention completion and improvement in clinical and behavioral measures
will be useful for further development of DPPs for this population.
Original language | English |
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Article number | 339 |
Pages (from-to) | 1-10 |
Number of pages | 10 |
Journal | Trials |
Volume | 14 |
DOIs |
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Publication status | Published - 17 Oct 2013 |