@article{44baa06ba36742cbadf3a9839eb2d189,
title = "National predictors of influenza vaccine uptake in pregnancy: the FluMum prospective cohort study, Australia, 2012–2015",
abstract = "Objective: Ascertain predictors of inactivated influenza vaccine (IIV) uptake in pregnancy in mother–infant pairs from six Australian sites over four consecutive influenza seasons (2012–2015). Methods: Prospective observational cohort study calculating proportions of unvaccinated and vaccinated pregnancies. Multivariable logistic regression calculating adjusted odds ratios (aOR) and 95% confidence intervals (95%CI) to determine demographic, pregnancy and birth characteristics as predictors of IIV uptake in pregnancy. Results: Uptake of IIV was 36% (n=3,651/9,878) with only 3–4% during the first trimester. Validation of IIV receipt was obtained for 77% of vaccinated participants. Predictors of IIV uptake in pregnancy were: healthcare provider recommendation to have IIV during pregnancy (aOR 7.04 [95%CI 5.83-8.50]): GP (aOR 4.12 [95%CI 3.43-4.98]), obstetrician (aOR 4.41 [95%CI 3.45-5.64]), midwife (aOR 1.88 [95%CI 1.51-2.36]); previous IIV within 12 months of their current pregnancy (aOR 2.87 [95%CI 2.36-3.50]); and pertussis vaccination during the current pregnancy (aOR 4.88 [95%CI 4.08-5.83]). Conclusions and implications for public health: Healthcare provider discussions with pregnant women about the risks associated with influenza infection during pregnancy and early infancy and evidence about the safety and effectiveness of IIV are required. Recommending and offering IIV in pregnancy needs to be included in these discussions to improve uptake.",
keywords = "influenza, predictors, pregnancy, vaccination",
author = "Lisa McHugh and O'Grady, {Kerry Ann F.} and Terry Nolan and Richmond, {Peter C.} and Nicholas Wood and Marshall, {Helen S.} and Lambert, {Stephen B.} and Chatfield, {Mark D.} and Perrett, {Kirsten P.} and Paula Binks and Binks, {Michael J.} and Andrews, {Ross M.}",
note = "Funding Information: This project was funded via a National Health and Medical Research Council (NHMRC) Project Grant (APP 1020035). Lisa McHugh is funded through the NHMRC Council Centre of Research Excellence (CRE), the Australian Partnership for Preparedness Research on Infectious Disease Emergencies (APPRISE APP1116530) as an APPRISE Research Fellow. During the project, Kerry‐Ann O'Grady was supported by NHMRC Early Career and Career Development Fellowships (490338 and APP1045157). Helen Marshall is supported by an NHMRC Practitioner Fellowship APP1155066, Nicholas Wood is supported by an NHMRC Career Development Fellowship APP1142783, Kirsten Perrett is supported by a Melbourne Children's Clinician Scientist Fellowship. Paula Binks is supported by an NHMRC postgraduate scholarship (APP1190983). Michael Binks is funded by an NHMRC {\textquoteleft}Hot North{\textquoteright} Career Development Fellowship (GNT 1131932). Funding Information: The authors have stated the following conflicts of interest: HM is an investigator on industry sponsored studies of investigational vaccines. Her institution has received funding for investigator‐led research from GSK, Pfizer and Sanofi‐Pasteur. She receives no personal payments from Industry. KPP is an investigator on industry sponsored studies of investigational vaccines. Her institution has received funding from GSK, MedImmune and Novavax outside the submitted work. She receives no personal payments from Industry. PCR is an investigator on industry sponsored studies of Investigational vaccines. His institution has received funding for investigator‐led research from GSK and Novartis outside the submitted work and for his participation in advisory boards for Astra Zeneca, GSK, Novavax, Pfizer and Sanofi. He receives no personal payments from Industry. Publisher Copyright: {\textcopyright} 2021 The Authors Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2021",
month = aug,
doi = "10.1111/1753-6405.13130",
language = "English",
journal = "Australian and New Zealand Journal of Public Health",
issn = "1326-0200",
publisher = "Public Health Association of Australia",
}