Natural Human Infections With Plasmodium cynomolgi and Other Malaria Species in an Elimination Setting in Sabah, Malaysia

Lynn Grignard, Sonal Shah, Tock H. Chua, Timothy William, Chris J. Drakeley, Kimberly M. Fornace

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    Abstract

    To determine the presence and species composition of malaria infections, we screened a subset of samples collected during a cross-sectional survey in Northern Sabah, Malaysia using highly sensitive molecular techniques. Results identified 54 asymptomatic submicroscopic malaria infections, including a large cluster of Plasmodium falciparum and 3 P. knowlesi infections. We additionally identified 2 monoinfections with the zoonotic malaria Plasmodium cynomolgi, both in individuals reporting no history of forest activities or contact with macaques. Results highlight the need for improved surveillance strategies to detect these infections and determine public health impacts.

    Original languageEnglish
    Pages (from-to)1946-1949
    Number of pages4
    JournalThe Journal of infectious diseases
    Volume220
    Issue number12
    Early online date16 Aug 2019
    DOIs
    Publication statusPublished - 15 Dec 2019

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