Non-CF Bronchiectasis

Dustin Mills; Anne B. Chang; Julie M. Marchant

doi:10.1007/978-3-031-42859-3_5

Non-CF Bronchiectasis

Dustin Mills, Anne B. Chang, Julie M. Marchant

Child and Maternal Health

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Bronchiectasis is a disease of recurrent wet cough and acute respiratory exacerbations with objective confirmation by abnormal bronchial dilatation on chest computed tomography scans. There is strong evidence that macrolide maintenance therapy reduces the frequency of respiratory exacerbations in both children and adults. This chapter will focus on the clinical use of macrolides in bronchiectasis in both adults and children, in relation to current guidelines, evidence and key recommendations, as well as exploring risks of long-term therapy and future research priorities.

Original language	English
Title of host publication	Macrolides as Immunomodulatory Agents
Editors	Bruce K. Rubin, Masaharu Shinkai
Place of Publication	Switzerland
Publisher	Springer Nature
Pages	93-113
Number of pages	21
Edition	1
ISBN (Electronic)	978-3-031-42859-3
DOIs	https://doi.org/10.1007/978-3-031-42859-3_5
Publication status	Published - 2024

Publication series

Name	Progress in Inflammation Research
Volume	92
ISSN (Print)	1422-7746
ISSN (Electronic)	2296-4525

Bibliographical note

Publisher Copyright:
© 2024, The Author(s), under exclusive license to Springer Nature Switzerland AG.

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10.1007/978-3-031-42859-3_5

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title = "Non-CF Bronchiectasis",

abstract = "Bronchiectasis is a disease of recurrent wet cough and acute respiratory exacerbations with objective confirmation by abnormal bronchial dilatation on chest computed tomography scans. There is strong evidence that macrolide maintenance therapy reduces the frequency of respiratory exacerbations in both children and adults. This chapter will focus on the clinical use of macrolides in bronchiectasis in both adults and children, in relation to current guidelines, evidence and key recommendations, as well as exploring risks of long-term therapy and future research priorities.",

keywords = "Azithromycin, Bronchiectasis, Macrolides, Maintenance antibiotics",

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AU - Chang, Anne B.

AU - Marchant, Julie M.

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AB - Bronchiectasis is a disease of recurrent wet cough and acute respiratory exacerbations with objective confirmation by abnormal bronchial dilatation on chest computed tomography scans. There is strong evidence that macrolide maintenance therapy reduces the frequency of respiratory exacerbations in both children and adults. This chapter will focus on the clinical use of macrolides in bronchiectasis in both adults and children, in relation to current guidelines, evidence and key recommendations, as well as exploring risks of long-term therapy and future research priorities.

KW - Azithromycin

KW - Bronchiectasis

KW - Macrolides

KW - Maintenance antibiotics

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A2 - Rubin, Bruce K.

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PB - Springer Nature

CY - Switzerland

ER -

Non-CF Bronchiectasis

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