TY - JOUR
T1 - Obstructive sleep apnoea and adherence to continuous positive airway therapy among Australian women
AU - Heraganahally, Subash S.
AU - Zaw, Kyi K.
AU - Tip, Sai
AU - Jing, Xinlin
AU - Mingi, Joy J.
AU - Howarth, Timothy
AU - Roy, Anil
AU - Falhammar, Henrik
AU - Sajkov, Dimitar
N1 - Funding Information:
We thank Ms Jenni Brotherton from Philips Respironics, Sleep Easy Centre, Darwin, for providing patients' CPAP compliance data for this study. We also thank all the administrative staff and sleep technologists, in particular Ms Tiziana Buysman, Mrs Elisha Mae Gamorot and Ms Charmain Beatriz Atos at Darwin Respiratory and Sleep health in contributing towards CPAP adherence data collection.
Publisher Copyright:
© 2020 Royal Australasian College of Physicians.
PY - 2022/3
Y1 - 2022/3
N2 - Background: Clinical characteristics of women with different obstructive sleep apnoea (OSA) severity and adherence to continuous positive airway pressure (CPAP) therapy have not been previously explored. Aims: To assess OSA prevalence, predictors, clinical and polysomnographic (PSG) characteristics and adherence to CPAP therapy among adult Australian women in a retrospective study. Methods: All female patients who underwent a diagnostic PSG between 2014 and 2015 were included. CPAP adherence was assessed during the study period between 2018 and 2019 using multiple regression models. Results: Among a total of 591 women included in this study (Aboriginal, n = 86), OSA was diagnosed in 458/591 (78%) patients; mild, moderate and severe OSA was present in 44%, 27% and 29% respectively. Older age, higher BMI and hypertension predicted the presence and severity of OSA. The Epworth Sleepiness Scale (ESS) score was not significantly different with (8 (5, 12)) or without (10 (5, 13)) OSA. PSG showed the rapid eye movement (REM) sleep-associated apnoea−hypopnea index (AHI) was higher with all severity of OSA. Adherence to CPAP therapy was noted in 171 (57%) patients; 47% mild, 57% moderate and 63% with severe OSA respectively. Three multiple regression models (clinical, PSG parameters, OSA severity, combined (clinical and PSG)) showed the combined model had the strongest predictive value and demonstrated that higher ESS and more severe oxygen desaturation were associated with CPAP adherence irrespective of OSA severity. Conclusions: Older age, higher BMI and the presence of hypertension predicted the presence of OSA. The REM sleep-related AHI was higher. Adherence to CPAP was associated with symptomatic OSA and severe oxygen desaturation.
AB - Background: Clinical characteristics of women with different obstructive sleep apnoea (OSA) severity and adherence to continuous positive airway pressure (CPAP) therapy have not been previously explored. Aims: To assess OSA prevalence, predictors, clinical and polysomnographic (PSG) characteristics and adherence to CPAP therapy among adult Australian women in a retrospective study. Methods: All female patients who underwent a diagnostic PSG between 2014 and 2015 were included. CPAP adherence was assessed during the study period between 2018 and 2019 using multiple regression models. Results: Among a total of 591 women included in this study (Aboriginal, n = 86), OSA was diagnosed in 458/591 (78%) patients; mild, moderate and severe OSA was present in 44%, 27% and 29% respectively. Older age, higher BMI and hypertension predicted the presence and severity of OSA. The Epworth Sleepiness Scale (ESS) score was not significantly different with (8 (5, 12)) or without (10 (5, 13)) OSA. PSG showed the rapid eye movement (REM) sleep-associated apnoea−hypopnea index (AHI) was higher with all severity of OSA. Adherence to CPAP therapy was noted in 171 (57%) patients; 47% mild, 57% moderate and 63% with severe OSA respectively. Three multiple regression models (clinical, PSG parameters, OSA severity, combined (clinical and PSG)) showed the combined model had the strongest predictive value and demonstrated that higher ESS and more severe oxygen desaturation were associated with CPAP adherence irrespective of OSA severity. Conclusions: Older age, higher BMI and the presence of hypertension predicted the presence of OSA. The REM sleep-related AHI was higher. Adherence to CPAP was associated with symptomatic OSA and severe oxygen desaturation.
KW - adherence
KW - continuous positive airway pressure
KW - female
KW - gender
KW - woman
UR - http://www.scopus.com/inward/record.url?scp=85098863984&partnerID=8YFLogxK
U2 - 10.1111/imj.15076
DO - 10.1111/imj.15076
M3 - Article
C2 - 33012105
AN - SCOPUS:85098863984
SN - 1444-0903
VL - 52
SP - 440
EP - 450
JO - Internal Medicine Journal
JF - Internal Medicine Journal
IS - 3
ER -