TY - JOUR
T1 - Oral health in patients with dementia
T2 - A meta-analysis of comparative and observational studies
AU - Zeng, Liang Nan
AU - Zong, Qian Qian
AU - Xu, Shi Wei
AU - An, Feng Rong
AU - Ungvari, Gabor S.
AU - Bressington, Daniel T.
AU - Cheung, Teris
AU - Qin, Ming Zhao
AU - Chen, Li Gang
AU - Xiang, Yu Tao
N1 - Funding Information:
All authors acknowledge that the material presented in this manuscript has not been previously published, nor is it simultaneously under consideration by any other journal. The study was supported by the University of Macau (MYRG2015‐00,230‐FHS; MYRG2016‐00,005‐FHS), National Key Research & Development Program of China (No. 2016YFC1307200), Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (No.ZYLX201607), and Beijing Municipal Administration of Hospitals' Ascent Plan (No. DFL20151801).
Funding Information:
All authors acknowledge that the material presented in this manuscript has not been previously published, nor is it simultaneously under consideration by any other journal. The study was supported by the University of Macau (MYRG2015-00,230-FHS; MYRG2016-00,005-FHS), National Key Research & Development Program of China (No. 2016YFC1307200), Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (No.ZYLX201607), and Beijing Municipal Administration of Hospitals' Ascent Plan (No. DFL20151801).
Publisher Copyright:
© 2020 John Wiley & Sons Ltd.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/4
Y1 - 2021/4
N2 - Objective: Poor oral health is common in dementia, but findings of epidemiological studies have been inconsistent. This meta-analysis examined oral health in patients with dementia diagnosed according to standardized diagnostic criteria. Methods: Six international databases (PubMed, EMBASE, PsycINFO, Medline, Cochrane Library, and Web of Science) were searched from their commencement date until 8 November 2018. Oral health was measured by the Remaining Teeth (RT) and Decayed, Missing, and Filled Teeth (DMFT) Index. The mean differences (MD) and 95% confidence intervals (CI) of DMFT Index total and component scores were calculated using a random-effect model. Results: Twenty-four studies were included for analyses. The pooled DMFT Index was 23.48 (95% CI: 22.34, 24.62), while the pooled score for each component was 2.38 (95% CI: 1.56, 3.20) in decayed teeth (DT), 18.39 (95% CI: 15.92, 20.87) in missing teeth (MT), 2.29 (95% CI: 0.62, 3.95) in filled teeth (FT), and 11.59 (95% CI: 9.14, 14.05) in RT. Compared to controls, people with dementia had significantly a higher DMFT Index total score (MD = 3.80, 95% CI: 2.21, 5.39, p < 0.00,001), and significantly lower number of RT (MD = −3.15, 95% CI: −4.23, −2.06, p < 0.00,001). Subgroup analyses revealed that higher DMFT Index score was significantly associated with year of survey (>2010), study design (case-control study), percentage of females (≤54.3), and the Mini Mental State Examination score (≤18.2). Higher MT score was significantly associated with study design (cross-sectional study), and lower FT score was significantly associated with year of survey (>2010). Conclusions: Oral health was significantly poorer in people with dementia compared with controls. Regular screening and effective treatment should be implemented for this population.
AB - Objective: Poor oral health is common in dementia, but findings of epidemiological studies have been inconsistent. This meta-analysis examined oral health in patients with dementia diagnosed according to standardized diagnostic criteria. Methods: Six international databases (PubMed, EMBASE, PsycINFO, Medline, Cochrane Library, and Web of Science) were searched from their commencement date until 8 November 2018. Oral health was measured by the Remaining Teeth (RT) and Decayed, Missing, and Filled Teeth (DMFT) Index. The mean differences (MD) and 95% confidence intervals (CI) of DMFT Index total and component scores were calculated using a random-effect model. Results: Twenty-four studies were included for analyses. The pooled DMFT Index was 23.48 (95% CI: 22.34, 24.62), while the pooled score for each component was 2.38 (95% CI: 1.56, 3.20) in decayed teeth (DT), 18.39 (95% CI: 15.92, 20.87) in missing teeth (MT), 2.29 (95% CI: 0.62, 3.95) in filled teeth (FT), and 11.59 (95% CI: 9.14, 14.05) in RT. Compared to controls, people with dementia had significantly a higher DMFT Index total score (MD = 3.80, 95% CI: 2.21, 5.39, p < 0.00,001), and significantly lower number of RT (MD = −3.15, 95% CI: −4.23, −2.06, p < 0.00,001). Subgroup analyses revealed that higher DMFT Index score was significantly associated with year of survey (>2010), study design (case-control study), percentage of females (≤54.3), and the Mini Mental State Examination score (≤18.2). Higher MT score was significantly associated with study design (cross-sectional study), and lower FT score was significantly associated with year of survey (>2010). Conclusions: Oral health was significantly poorer in people with dementia compared with controls. Regular screening and effective treatment should be implemented for this population.
KW - decayed
KW - dementia
KW - filled teeth
KW - meta-analysis
KW - missing
KW - oral health
UR - http://www.scopus.com/inward/record.url?scp=85096705687&partnerID=8YFLogxK
U2 - 10.1002/gps.5453
DO - 10.1002/gps.5453
M3 - Review article
C2 - 33105039
AN - SCOPUS:85096705687
VL - 36
SP - 467
EP - 478
JO - International Journal of Geriatric Psychiatry
JF - International Journal of Geriatric Psychiatry
SN - 0885-6230
IS - 4
ER -