Oxygen transport capacity in the air-breathing fish, Megalops cyprinoides

compensations for strenuous exercise

R Wells, John Baldwin, Roger Seymour, R Baudinette, Keith Christian, Michael Bennett

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    Tarpon have high resting or routine hematocrits (Hct) (37.6±3.4%) and hemoglobin concentrations (120.6±7.3 g l -1) that increased significantly following bouts of angling-induced exercise (51.9±3.7% and 142.8±13.5 g l -1, respectively). Strenuous exercise was accompanied by an approximately tenfold increase in blood lactate and a muscle metabolite profile indicative of a high energy demand teleost. Routine blood values were quickly restored only when this facultative air-breathing fish was given access to atmospheric air. In vitro studies of oxygen transport capacity, a function of carrying capacity and viscosity, revealed that the optimal Hct range corresponded to that observed in fish under routine behaviour. During strenuous exercise however, further increase in viscosity was largely offset by a pronounced reduction in the shear-dependence of blood which conformed closely to an ideal Newtonian fluid. The mechanism for this behaviour of the erythrocytes appears to involve the activation of surface adrenergic receptors because pre-treatment with propranolol abolished the response. High levels of activity in tarpon living in hypoxic habitats are therefore supported by an elevated Hct with adrenergically mediated viscosity reduction, and air-breathing behaviour that enables rapid metabolic recovery. © 2002 Elsevier Science Inc. All rights reserved.
    Original languageEnglish
    Pages (from-to)45-53
    Number of pages9
    JournalComparative biochemistry and physiology. Part A, Molecular & integrative physiology
    Volume134
    Issue number1
    DOIs
    Publication statusPublished - 2003

    Fingerprint

    Hematocrit
    Viscosity
    Fish
    Respiration
    Fishes
    Blood
    Air
    Oxygen
    Conservation of Natural Resources
    Metabolites
    Propranolol
    Adrenergic Receptors
    Ecosystem
    Muscle
    Lactic Acid
    Hemoglobins
    Erythrocytes
    Chemical activation
    Recovery
    Muscles

    Cite this

    @article{7581222726434e9aa798b4f0e60f9570,
    title = "Oxygen transport capacity in the air-breathing fish, Megalops cyprinoides: compensations for strenuous exercise",
    abstract = "Tarpon have high resting or routine hematocrits (Hct) (37.6±3.4{\%}) and hemoglobin concentrations (120.6±7.3 g l -1) that increased significantly following bouts of angling-induced exercise (51.9±3.7{\%} and 142.8±13.5 g l -1, respectively). Strenuous exercise was accompanied by an approximately tenfold increase in blood lactate and a muscle metabolite profile indicative of a high energy demand teleost. Routine blood values were quickly restored only when this facultative air-breathing fish was given access to atmospheric air. In vitro studies of oxygen transport capacity, a function of carrying capacity and viscosity, revealed that the optimal Hct range corresponded to that observed in fish under routine behaviour. During strenuous exercise however, further increase in viscosity was largely offset by a pronounced reduction in the shear-dependence of blood which conformed closely to an ideal Newtonian fluid. The mechanism for this behaviour of the erythrocytes appears to involve the activation of surface adrenergic receptors because pre-treatment with propranolol abolished the response. High levels of activity in tarpon living in hypoxic habitats are therefore supported by an elevated Hct with adrenergically mediated viscosity reduction, and air-breathing behaviour that enables rapid metabolic recovery. {\circledC} 2002 Elsevier Science Inc. All rights reserved.",
    keywords = "adrenergic receptor, propranolol, animal experiment, article, atmosphere, blood examination, blood viscosity, breathing, cell activity, controlled study, energy, erythrocyte, exercise, fish, hematocrit, hemoglobin determination, lactate blood level, muscle metabolism, nonhuman, normal value, oxygen transport, teleost, Adaptation, Physiological, Adenosine Triphosphate, Air, Animals, Blood Viscosity, Erythrocytes, Exertion, Fishes, Hematocrit, Hemoglobins, Oxygen, Respiration, Stress, Megalops atlanticus, Megalops cyprinoides, Teleostei",
    author = "R Wells and John Baldwin and Roger Seymour and R Baudinette and Keith Christian and Michael Bennett",
    year = "2003",
    doi = "10.1016/S1095-6433(02)00179-4",
    language = "English",
    volume = "134",
    pages = "45--53",
    journal = "Comparative biochemistry and physiology. Part A, Molecular & integrative physiology",
    issn = "1095-6433",
    publisher = "Elsevier",
    number = "1",

    }

    Oxygen transport capacity in the air-breathing fish, Megalops cyprinoides : compensations for strenuous exercise. / Wells, R; Baldwin, John; Seymour, Roger; Baudinette, R; Christian, Keith; Bennett, Michael.

    In: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 134, No. 1, 2003, p. 45-53.

    Research output: Contribution to journalArticleResearchpeer-review

    TY - JOUR

    T1 - Oxygen transport capacity in the air-breathing fish, Megalops cyprinoides

    T2 - compensations for strenuous exercise

    AU - Wells, R

    AU - Baldwin, John

    AU - Seymour, Roger

    AU - Baudinette, R

    AU - Christian, Keith

    AU - Bennett, Michael

    PY - 2003

    Y1 - 2003

    N2 - Tarpon have high resting or routine hematocrits (Hct) (37.6±3.4%) and hemoglobin concentrations (120.6±7.3 g l -1) that increased significantly following bouts of angling-induced exercise (51.9±3.7% and 142.8±13.5 g l -1, respectively). Strenuous exercise was accompanied by an approximately tenfold increase in blood lactate and a muscle metabolite profile indicative of a high energy demand teleost. Routine blood values were quickly restored only when this facultative air-breathing fish was given access to atmospheric air. In vitro studies of oxygen transport capacity, a function of carrying capacity and viscosity, revealed that the optimal Hct range corresponded to that observed in fish under routine behaviour. During strenuous exercise however, further increase in viscosity was largely offset by a pronounced reduction in the shear-dependence of blood which conformed closely to an ideal Newtonian fluid. The mechanism for this behaviour of the erythrocytes appears to involve the activation of surface adrenergic receptors because pre-treatment with propranolol abolished the response. High levels of activity in tarpon living in hypoxic habitats are therefore supported by an elevated Hct with adrenergically mediated viscosity reduction, and air-breathing behaviour that enables rapid metabolic recovery. © 2002 Elsevier Science Inc. All rights reserved.

    AB - Tarpon have high resting or routine hematocrits (Hct) (37.6±3.4%) and hemoglobin concentrations (120.6±7.3 g l -1) that increased significantly following bouts of angling-induced exercise (51.9±3.7% and 142.8±13.5 g l -1, respectively). Strenuous exercise was accompanied by an approximately tenfold increase in blood lactate and a muscle metabolite profile indicative of a high energy demand teleost. Routine blood values were quickly restored only when this facultative air-breathing fish was given access to atmospheric air. In vitro studies of oxygen transport capacity, a function of carrying capacity and viscosity, revealed that the optimal Hct range corresponded to that observed in fish under routine behaviour. During strenuous exercise however, further increase in viscosity was largely offset by a pronounced reduction in the shear-dependence of blood which conformed closely to an ideal Newtonian fluid. The mechanism for this behaviour of the erythrocytes appears to involve the activation of surface adrenergic receptors because pre-treatment with propranolol abolished the response. High levels of activity in tarpon living in hypoxic habitats are therefore supported by an elevated Hct with adrenergically mediated viscosity reduction, and air-breathing behaviour that enables rapid metabolic recovery. © 2002 Elsevier Science Inc. All rights reserved.

    KW - adrenergic receptor

    KW - propranolol

    KW - animal experiment

    KW - article

    KW - atmosphere

    KW - blood examination

    KW - blood viscosity

    KW - breathing

    KW - cell activity

    KW - controlled study

    KW - energy

    KW - erythrocyte

    KW - exercise

    KW - fish

    KW - hematocrit

    KW - hemoglobin determination

    KW - lactate blood level

    KW - muscle metabolism

    KW - nonhuman

    KW - normal value

    KW - oxygen transport

    KW - teleost

    KW - Adaptation, Physiological

    KW - Adenosine Triphosphate

    KW - Air

    KW - Animals

    KW - Blood Viscosity

    KW - Erythrocytes

    KW - Exertion

    KW - Fishes

    KW - Hematocrit

    KW - Hemoglobins

    KW - Oxygen

    KW - Respiration

    KW - Stress

    KW - Megalops atlanticus

    KW - Megalops cyprinoides

    KW - Teleostei

    UR - http://www.scopus.com/inward/record.url?scp=0037223387&partnerID=8YFLogxK

    U2 - 10.1016/S1095-6433(02)00179-4

    DO - 10.1016/S1095-6433(02)00179-4

    M3 - Article

    VL - 134

    SP - 45

    EP - 53

    JO - Comparative biochemistry and physiology. Part A, Molecular & integrative physiology

    JF - Comparative biochemistry and physiology. Part A, Molecular & integrative physiology

    SN - 1095-6433

    IS - 1

    ER -