Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 207-217 |
| Number of pages | 11 |
| Journal | Epidemiology and Infection |
| Volume | 146 |
| Issue number | 2 |
| Early online date | 2017 |
| DOIs | |
| Publication status | Published - Jan 2018 |
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Pertussis epidemiology prior to the introduction of a maternal vaccination program, Queensland Australia. / Mchugh, Lisa; Viney, Kerri A.; Andrews, Ross; Lambert, Stephen B.
In: Epidemiology and Infection, Vol. 146, No. 2, 01.2018, p. 207-217.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Pertussis epidemiology prior to the introduction of a maternal vaccination program, Queensland Australia
AU - Mchugh, Lisa
AU - Viney, Kerri A.
AU - Andrews, Ross
AU - Lambert, Stephen B
PY - 2018/1
Y1 - 2018/1
N2 - Pertussis morbidity is highest in infants too young to be fully protected by routine vaccination schedules. Alternate vaccine strategies are required to maximise protection in this age-group. To understand baseline pertussis epidemiology prior to the introduction of the maternal pertussis vaccination program in 2014, we conducted a retrospective case series analyses of 53 901 notifications and temporal trends from 1997 to 2014. Notifications were highest in infants younger than 4 months of age and highest annual notification rates in infants younger than 1 month of age (308/100 000 per year). Amongst Aboriginal and Torres Strait Islander infants aged younger than 1 month, this rate was 576/100 000 per year. Notification rates were 40% higher amongst women 15–44 years, 62·4/100 000 population compared with men (44·5/100 000) and 90% higher in Aboriginal and Torres Strait Islander women of the same age (38·2/100 000) compared with men (19·7/100 000). Six infant deaths were identified, all younger than 2 months of age. Monitoring epidemiology in at-risk groups – infants too young to be vaccinated, women of childbearing age and Aboriginal and Torres Strait Islander peoples – following implementation of the maternal pertussis vaccination program will be important to assess its impact and safety.
AB - Pertussis morbidity is highest in infants too young to be fully protected by routine vaccination schedules. Alternate vaccine strategies are required to maximise protection in this age-group. To understand baseline pertussis epidemiology prior to the introduction of the maternal pertussis vaccination program in 2014, we conducted a retrospective case series analyses of 53 901 notifications and temporal trends from 1997 to 2014. Notifications were highest in infants younger than 4 months of age and highest annual notification rates in infants younger than 1 month of age (308/100 000 per year). Amongst Aboriginal and Torres Strait Islander infants aged younger than 1 month, this rate was 576/100 000 per year. Notification rates were 40% higher amongst women 15–44 years, 62·4/100 000 population compared with men (44·5/100 000) and 90% higher in Aboriginal and Torres Strait Islander women of the same age (38·2/100 000) compared with men (19·7/100 000). Six infant deaths were identified, all younger than 2 months of age. Monitoring epidemiology in at-risk groups – infants too young to be vaccinated, women of childbearing age and Aboriginal and Torres Strait Islander peoples – following implementation of the maternal pertussis vaccination program will be important to assess its impact and safety.
UR - http://www.scopus.com/inward/record.url?scp=85038031386&partnerID=8YFLogxK
U2 - 10.1017/S0950268817002722
DO - 10.1017/S0950268817002722
M3 - Article
VL - 146
SP - 207
EP - 217
JO - Epidemiology and Infection
JF - Epidemiology and Infection
SN - 0950-2688
IS - 2
ER -