Predicting memory: A prospective readout for malaria vaccines?

Gabriela Minigo, Karen Scalzo, Katie L. Flanagan, Magdalena Plebanski

Research output: Contribution to journalShort surveypeer-review


Malaria vaccines aim to induce long lasting protective immunity. Bejon and colleagues propose that levels of rapidly induced (effector memory) interleukin-2 and interferon gamma producing T-cells after vaccination with leading pre-erythrocytic stage vaccines predict the induction of resting memory responses (central memory). Herein we discuss Bejon's findings in the context of current thinking on the generation and maintenance of T cell memory, with particular emphasis on the role of cytokines.

Original languageEnglish
Pages (from-to)341-343
Number of pages3
JournalTrends in Parasitology
Issue number8
Publication statusPublished - Aug 2007
Externally publishedYes


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