Predicting memory: A prospective readout for malaria vaccines?

Gabriela Minigo; Karen Scalzo; Katie L. Flanagan; Magdalena Plebanski

doi:10.1016/j.pt.2007.06.006

Predicting memory: A prospective readout for malaria vaccines?

Gabriela Minigo, Karen Scalzo, Katie L. Flanagan, Magdalena Plebanski

Research output: Contribution to journal › Short survey › peer-review

Abstract

Malaria vaccines aim to induce long lasting protective immunity. Bejon and colleagues propose that levels of rapidly induced (effector memory) interleukin-2 and interferon gamma producing T-cells after vaccination with leading pre-erythrocytic stage vaccines predict the induction of resting memory responses (central memory). Herein we discuss Bejon's findings in the context of current thinking on the generation and maintenance of T cell memory, with particular emphasis on the role of cytokines.

Original language	English
Pages (from-to)	341-343
Number of pages	3
Journal	Trends in Parasitology
Volume	23
Issue number	8
DOIs	https://doi.org/10.1016/j.pt.2007.06.006
Publication status	Published - Aug 2007
Externally published	Yes

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10.1016/j.pt.2007.06.006

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title = "Predicting memory: A prospective readout for malaria vaccines?",

abstract = "Malaria vaccines aim to induce long lasting protective immunity. Bejon and colleagues propose that levels of rapidly induced (effector memory) interleukin-2 and interferon gamma producing T-cells after vaccination with leading pre-erythrocytic stage vaccines predict the induction of resting memory responses (central memory). Herein we discuss Bejon's findings in the context of current thinking on the generation and maintenance of T cell memory, with particular emphasis on the role of cytokines.",

author = "Gabriela Minigo and Karen Scalzo and Flanagan, {Katie L.} and Magdalena Plebanski",

year = "2007",

month = aug,

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language = "English",

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AU - Minigo, Gabriela

AU - Scalzo, Karen

AU - Flanagan, Katie L.

AU - Plebanski, Magdalena

PY - 2007/8

Y1 - 2007/8

N2 - Malaria vaccines aim to induce long lasting protective immunity. Bejon and colleagues propose that levels of rapidly induced (effector memory) interleukin-2 and interferon gamma producing T-cells after vaccination with leading pre-erythrocytic stage vaccines predict the induction of resting memory responses (central memory). Herein we discuss Bejon's findings in the context of current thinking on the generation and maintenance of T cell memory, with particular emphasis on the role of cytokines.

AB - Malaria vaccines aim to induce long lasting protective immunity. Bejon and colleagues propose that levels of rapidly induced (effector memory) interleukin-2 and interferon gamma producing T-cells after vaccination with leading pre-erythrocytic stage vaccines predict the induction of resting memory responses (central memory). Herein we discuss Bejon's findings in the context of current thinking on the generation and maintenance of T cell memory, with particular emphasis on the role of cytokines.

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DO - 10.1016/j.pt.2007.06.006

M3 - Short survey

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AN - SCOPUS:34447529117

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JO - Trends in Parasitology

JF - Trends in Parasitology

SN - 0169-4758

IS - 8

ER -

Predicting memory: A prospective readout for malaria vaccines?

Abstract

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