Abstract
Actin-based motility of the melioidosis pathogen Burkholderia pseudomallei requires BimA. We report a high degree of conservation of bimA in 99 B. pseudomallei isolates from the area of endemicity. A geographically restricted subset of B. pseudomallei isolates harbored a B. mallei-like bimA allele (12.1%), confounding a differential diagnostic test based on amplification of species-specific bimA regions. Copyright � 2008, American Society for Microbiology. All Rights Reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 2418-2422 |
| Number of pages | 5 |
| Journal | Journal of Clinical Microbiology |
| Volume | 46 |
| Issue number | 7 |
| Publication status | Published - 2008 |
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Sitthidet, C., Stevens, J. M., Chantratitia, N., Currie, B., Peacock, S. J., Korbsrisate, S., & Stevens, M. (2008). Prevalence and Sequence Diversity of a Factor Required for Actin-Based Motility in Natural Populations of Burkholderia Species. Journal of Clinical Microbiology, 46(7), 2418-2422.