Prevalence of Anemia and Risk of Adverse Bleeding Effect of Drugs

Implication for Therapy

Ezekiel (Uba) Nwose

Research output: Contribution to journalArticleResearchpeer-review

Abstract

This study aimed to evaluate the progress in reduction of prevalence of anemia in rural Australia. It also investigates the prevalence of hypoviscosity in anaemia with a view to determine the fraction of anaemic patients at risk of drug-inducible exacerbation of anemia. Archived clinical pathology data ( = 1 3 0 , 3 5 4 ) for the period of 1999 to 2008 were utilized. The prevalence of anemia and hypoviscosity was evaluated by working out (i) the number that fell within anemia definition as a percentage of the population and (ii) the number that fell within hypoviscosity definition as a percentage of anemic patients. The prevalence in anemic diabetes and dyslipidaemia was further determined. There was progressive reduction in anemia from 6.1% to 3.2% over the ten years period. Prevalence of anemia is statistically significantly higher in males than in females ( < 0 . 0 0 0 1 ), but protein level is lower in anemic females than in anemic males ( < 0 . 0 1 ). The results further show that up to 75% of anemic patients may benefit from NSAID or salicylates. This paper highlights differences between genders. It suggests more concerted effort in men's health and speculates a new factor to investigate in women's health.
Original languageEnglish
Article number795439
Pages (from-to)1-5
Number of pages5
JournalAnemia
Volume2012
DOIs
Publication statusPublished - 2012
Externally publishedYes

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Anemia
Hemorrhage
Drug Therapy
Men's Health
Clinical Pathology
Salicylates
Women's Health
Non-Steroidal Anti-Inflammatory Agents
Dyslipidemias
Pharmaceutical Preparations
Population
Proteins

Cite this

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abstract = "This study aimed to evaluate the progress in reduction of prevalence of anemia in rural Australia. It also investigates the prevalence of hypoviscosity in anaemia with a view to determine the fraction of anaemic patients at risk of drug-inducible exacerbation of anemia. Archived clinical pathology data ( = 1 3 0 , 3 5 4 ) for the period of 1999 to 2008 were utilized. The prevalence of anemia and hypoviscosity was evaluated by working out (i) the number that fell within anemia definition as a percentage of the population and (ii) the number that fell within hypoviscosity definition as a percentage of anemic patients. The prevalence in anemic diabetes and dyslipidaemia was further determined. There was progressive reduction in anemia from 6.1{\%} to 3.2{\%} over the ten years period. Prevalence of anemia is statistically significantly higher in males than in females ( < 0 . 0 0 0 1 ), but protein level is lower in anemic females than in anemic males ( < 0 . 0 1 ). The results further show that up to 75{\%} of anemic patients may benefit from NSAID or salicylates. This paper highlights differences between genders. It suggests more concerted effort in men's health and speculates a new factor to investigate in women's health.",
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Prevalence of Anemia and Risk of Adverse Bleeding Effect of Drugs : Implication for Therapy. / Nwose, Ezekiel (Uba).

In: Anemia, Vol. 2012, 795439, 2012, p. 1-5.

Research output: Contribution to journalArticleResearchpeer-review

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