Prognostic significance of Lymph Node Ratio (LNR): Clinical insights and strategies for routine clinical practice

Rama Jayaraj; Chellan Kumarasamy; Shanthi Sabarimurugan; Madurantakam Royam Madhav; Kartik Lakhotiya; Ramesh Nachimuthu; K. M. Gothandam; Suja Samiappan

doi:10.1016/j.oraloncology.2019.02.012

Prognostic significance of Lymph Node Ratio (LNR): Clinical insights and strategies for routine clinical practice

Rama Jayaraj, Chellan Kumarasamy, Shanthi Sabarimurugan, Madurantakam Royam Madhav, Kartik Lakhotiya, Ramesh Nachimuthu, K. M. Gothandam, Suja Samiappan

CDU College of Health and Human Sciences

Research output: Contribution to journal › Letter › peer-review

Abstract

To the Editor,

Huang and colleagues have provided some valuable insights into the utility of Lymph Node Ratio (LNR) as a prognostic variable in Oral Squamous Cell Carcinoma, via their systematic review and meta-analysis study, published in the Journal of Oral Oncology [1]. Using the results of the study, the authors draw upon the conclusion that LNR may be a viable independent biomarker in OSCC. Although these conclusions are valid in the context of a said singular study conducted by Huang et al., other studies have presented varying clinical results and findings. We believe that highlighting these studies should be able to provide a better perspective on the clinical considerations of Huang and colleagues’ study.

Original language	English
Pages (from-to)	125-127
Number of pages	3
Journal	Oral Oncology
Volume	91
DOIs	https://doi.org/10.1016/j.oraloncology.2019.02.012
Publication status	Published - Apr 2019

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10.1016/j.oraloncology.2019.02.012

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title = "Prognostic significance of Lymph Node Ratio (LNR): Clinical insights and strategies for routine clinical practice",

abstract = "To the Editor,Huang and colleagues have provided some valuable insights into the utility of Lymph Node Ratio (LNR) as a prognostic variable in Oral Squamous Cell Carcinoma, via their systematic review and meta-analysis study, published in the Journal of Oral Oncology [1]. Using the results of the study, the authors draw upon the conclusion that LNR may be a viable independent biomarker in OSCC. Although these conclusions are valid in the context of a said singular study conducted by Huang et al., other studies have presented varying clinical results and findings. We believe that highlighting these studies should be able to provide a better perspective on the clinical considerations of Huang and colleagues{\textquoteright} study.",

author = "Rama Jayaraj and Chellan Kumarasamy and Shanthi Sabarimurugan and Madhav, {Madurantakam Royam} and Kartik Lakhotiya and Ramesh Nachimuthu and Gothandam, {K. M.} and Suja Samiappan",

year = "2019",

month = apr,

doi = "10.1016/j.oraloncology.2019.02.012",

language = "English",

volume = "91",

pages = "125--127",

journal = "Oral Oncology",

issn = "1368-8375",

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TY - JOUR

T1 - Prognostic significance of Lymph Node Ratio (LNR)

T2 - Clinical insights and strategies for routine clinical practice

AU - Jayaraj, Rama

AU - Kumarasamy, Chellan

AU - Sabarimurugan, Shanthi

AU - Madhav, Madurantakam Royam

AU - Lakhotiya, Kartik

AU - Nachimuthu, Ramesh

AU - Gothandam, K. M.

AU - Samiappan, Suja

PY - 2019/4

Y1 - 2019/4

N2 - To the Editor,Huang and colleagues have provided some valuable insights into the utility of Lymph Node Ratio (LNR) as a prognostic variable in Oral Squamous Cell Carcinoma, via their systematic review and meta-analysis study, published in the Journal of Oral Oncology [1]. Using the results of the study, the authors draw upon the conclusion that LNR may be a viable independent biomarker in OSCC. Although these conclusions are valid in the context of a said singular study conducted by Huang et al., other studies have presented varying clinical results and findings. We believe that highlighting these studies should be able to provide a better perspective on the clinical considerations of Huang and colleagues’ study.

AB - To the Editor,Huang and colleagues have provided some valuable insights into the utility of Lymph Node Ratio (LNR) as a prognostic variable in Oral Squamous Cell Carcinoma, via their systematic review and meta-analysis study, published in the Journal of Oral Oncology [1]. Using the results of the study, the authors draw upon the conclusion that LNR may be a viable independent biomarker in OSCC. Although these conclusions are valid in the context of a said singular study conducted by Huang et al., other studies have presented varying clinical results and findings. We believe that highlighting these studies should be able to provide a better perspective on the clinical considerations of Huang and colleagues’ study.

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U2 - 10.1016/j.oraloncology.2019.02.012

DO - 10.1016/j.oraloncology.2019.02.012

M3 - Letter

C2 - 30792068

AN - SCOPUS:85063284183

VL - 91

SP - 125

EP - 127

JO - Oral Oncology

JF - Oral Oncology

SN - 1368-8375

ER -

Prognostic significance of Lymph Node Ratio (LNR): Clinical insights and strategies for routine clinical practice

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