Prognostic significance of Lymph Node Ratio (LNR)

Clinical insights and strategies for routine clinical practice

Rama Jayaraj, Chellan Kumarasamy, Shanthi Sabarimurugan, Madurantakam Royam Madhav, Kartik Lakhotiya, Ramesh Nachimuthu, K. M. Gothandam, Suja Samiappan

Research output: Contribution to journalLetterResearchpeer-review

Abstract

To the Editor,

Huang and colleagues have provided some valuable insights into the utility of Lymph Node Ratio (LNR) as a prognostic variable in Oral Squamous Cell Carcinoma, via their systematic review and meta-analysis study, published in the Journal of Oral Oncology [1]. Using the results of the study, the authors draw upon the conclusion that LNR may be a viable independent biomarker in OSCC. Although these conclusions are valid in the context of a said singular study conducted by Huang et al., other studies have presented varying clinical results and findings. We believe that highlighting these studies should be able to provide a better perspective on the clinical considerations of Huang and colleagues’ study.
Original languageEnglish
Pages (from-to)125-127
Number of pages3
JournalOral Oncology
Volume91
DOIs
Publication statusPublished - Apr 2019

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Lymph Nodes
Meta-Analysis
Squamous Cell Carcinoma
Biomarkers

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Jayaraj, R., Kumarasamy, C., Sabarimurugan, S., Madhav, M. R., Lakhotiya, K., Nachimuthu, R., ... Samiappan, S. (2019). Prognostic significance of Lymph Node Ratio (LNR): Clinical insights and strategies for routine clinical practice. Oral Oncology, 91, 125-127. https://doi.org/10.1016/j.oraloncology.2019.02.012
Jayaraj, Rama ; Kumarasamy, Chellan ; Sabarimurugan, Shanthi ; Madhav, Madurantakam Royam ; Lakhotiya, Kartik ; Nachimuthu, Ramesh ; Gothandam, K. M. ; Samiappan, Suja. / Prognostic significance of Lymph Node Ratio (LNR) : Clinical insights and strategies for routine clinical practice. In: Oral Oncology. 2019 ; Vol. 91. pp. 125-127.
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abstract = "To the Editor,Huang and colleagues have provided some valuable insights into the utility of Lymph Node Ratio (LNR) as a prognostic variable in Oral Squamous Cell Carcinoma, via their systematic review and meta-analysis study, published in the Journal of Oral Oncology [1]. Using the results of the study, the authors draw upon the conclusion that LNR may be a viable independent biomarker in OSCC. Although these conclusions are valid in the context of a said singular study conducted by Huang et al., other studies have presented varying clinical results and findings. We believe that highlighting these studies should be able to provide a better perspective on the clinical considerations of Huang and colleagues’ study.",
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Jayaraj, R, Kumarasamy, C, Sabarimurugan, S, Madhav, MR, Lakhotiya, K, Nachimuthu, R, Gothandam, KM & Samiappan, S 2019, 'Prognostic significance of Lymph Node Ratio (LNR): Clinical insights and strategies for routine clinical practice', Oral Oncology, vol. 91, pp. 125-127. https://doi.org/10.1016/j.oraloncology.2019.02.012

Prognostic significance of Lymph Node Ratio (LNR) : Clinical insights and strategies for routine clinical practice. / Jayaraj, Rama; Kumarasamy, Chellan; Sabarimurugan, Shanthi; Madhav, Madurantakam Royam; Lakhotiya, Kartik; Nachimuthu, Ramesh; Gothandam, K. M.; Samiappan, Suja.

In: Oral Oncology, Vol. 91, 04.2019, p. 125-127.

Research output: Contribution to journalLetterResearchpeer-review

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T1 - Prognostic significance of Lymph Node Ratio (LNR)

T2 - Clinical insights and strategies for routine clinical practice

AU - Jayaraj, Rama

AU - Kumarasamy, Chellan

AU - Sabarimurugan, Shanthi

AU - Madhav, Madurantakam Royam

AU - Lakhotiya, Kartik

AU - Nachimuthu, Ramesh

AU - Gothandam, K. M.

AU - Samiappan, Suja

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AB - To the Editor,Huang and colleagues have provided some valuable insights into the utility of Lymph Node Ratio (LNR) as a prognostic variable in Oral Squamous Cell Carcinoma, via their systematic review and meta-analysis study, published in the Journal of Oral Oncology [1]. Using the results of the study, the authors draw upon the conclusion that LNR may be a viable independent biomarker in OSCC. Although these conclusions are valid in the context of a said singular study conducted by Huang et al., other studies have presented varying clinical results and findings. We believe that highlighting these studies should be able to provide a better perspective on the clinical considerations of Huang and colleagues’ study.

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JO - Oral Oncology

JF - Oral Oncology

SN - 1368-8375

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