Prostatic abscess due to burkholderia pseudomallei: Facilitating diagnosis to optimize management

Jowita Kozlowska, Simon Smith, Jay Roberts, Simon Pridgeon, Josh Hanson

    Research output: Contribution to journalComment/debate

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    Abstract

    Prostatic involvement is common in men with melioidosis. Indeed, some clinicians recommend radiological screening of all male patients as an undrained prostatic abscess may result in relapse of this potentially fatal disease. However, sophisticated medical imaging is frequently unavailable in the remote and resource-poor locations where patients are managed. In this retrospective study from Queensland, Australia, 22/144 (15%) men with melioidosis had a radiologically confirmed prostatic abscess. The absence of urinary symptoms had a negative predictive value (NPV) (95% confidence interval [CI]) for prostatic abscess of 96% (90-99%), whereas a urinary leukocyte count of < 50 × 106/L had an NPV (95% CI) of 100% (94-100%). A simple clinical history and basic laboratory investigations appear to exclude significant prostatic involvement relatively reliably and might be used to identify patients in whom radiological evaluation of the prostate is unnecessary. This may be particularly helpful in locations where radiological support is limited.

    Original languageEnglish
    Pages (from-to)227-230
    Number of pages4
    JournalAmerican Journal of Tropical Medicine and Hygiene
    Volume98
    Issue number1
    DOIs
    Publication statusPublished - 1 Jan 2018

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