RAPD analysis of isolates of Burkholderia pseudomallei from patients with recurrent melioidosis

A. Haase, A. Melder, H. Smith-Vaughan, D. Kemp, B. Currie

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Twenty-seven isolates of Burholderia pseudomallei (formerly Pseudomonas pseudomallei) from ten patients with recurrent melioidosis were analysed by RAPD. In two cases RAPD patterns in recurrent isolates differed from the original isolates; one was considered a likely reinfection while the other may represent relapse from one of two strains initially infecting the patient. In two cases where a change in antibiotic resistance had occurred between original and relapse isolates, slight changes in RAPD patterns were found with one of the four primers used. In the other six cases the relapse was clearly due to the original strain re-emerging unchanged, with identical RAPD patterns with all four primers.

    Original languageEnglish
    Pages (from-to)115-121
    Number of pages7
    JournalEpidemiology and Infection
    Volume115
    Issue number1
    DOIs
    Publication statusPublished - Aug 1995

    Fingerprint

    Dive into the research topics of 'RAPD analysis of isolates of Burkholderia pseudomallei from patients with recurrent melioidosis'. Together they form a unique fingerprint.

    Cite this