Room Temperature, Transition-Metal-Free Arylation of Alcohols with Aryl Bromides

Da Liang Zhu; Jie Li; Qi Wu; Yanqing Wang; David Young; Hong Xi Li

doi:10.1055/a-1932-6146

Room Temperature, Transition-Metal-Free Arylation of Alcohols with Aryl Bromides

Da Liang Zhu, Jie Li, Qi Wu, Yanqing Wang, David Young, Hong Xi Li

Research output: Contribution to journal › Article › peer-review

Abstract

Sodium t-butoxide promotes the efficient etherification of alcohols with aryl bromides at room temperature. This simple procedure has a broad substrate scope, providing a practical pathway to aryl alkyl ethers in good yields without the addition of any transition metal species.

Original language	English
Pages (from-to)	637-646
Number of pages	10
Journal	Synthesis (Germany)
Volume	55
DOIs	https://doi.org/10.1055/a-1932-6146
Publication status	E-pub ahead of print - 2022

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title = "Room Temperature, Transition-Metal-Free Arylation of Alcohols with Aryl Bromides",

abstract = "Sodium t-butoxide promotes the efficient etherification of alcohols with aryl bromides at room temperature. This simple procedure has a broad substrate scope, providing a practical pathway to aryl alkyl ethers in good yields without the addition of any transition metal species.",

keywords = "Alcohols, Aryl alkyl ethers, Aryl bromides, Mild conditions, Transition-metal-free",

author = "Zhu, {Da Liang} and Jie Li and Qi Wu and Yanqing Wang and David Young and Li, {Hong Xi}",

year = "2022",

doi = "10.1055/a-1932-6146",

language = "English",

volume = "55",

pages = "637--646",

journal = "Synthesis (Germany)",

issn = "0039-7881",

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T1 - Room Temperature, Transition-Metal-Free Arylation of Alcohols with Aryl Bromides

AU - Zhu, Da Liang

AU - Li, Jie

AU - Wu, Qi

AU - Wang, Yanqing

AU - Young, David

AU - Li, Hong Xi

PY - 2022

Y1 - 2022

N2 - Sodium t-butoxide promotes the efficient etherification of alcohols with aryl bromides at room temperature. This simple procedure has a broad substrate scope, providing a practical pathway to aryl alkyl ethers in good yields without the addition of any transition metal species.

AB - Sodium t-butoxide promotes the efficient etherification of alcohols with aryl bromides at room temperature. This simple procedure has a broad substrate scope, providing a practical pathway to aryl alkyl ethers in good yields without the addition of any transition metal species.

KW - Alcohols

KW - Aryl alkyl ethers

KW - Aryl bromides

KW - Mild conditions

KW - Transition-metal-free

UR - http://www.scopus.com/inward/record.url?scp=85137627909&partnerID=8YFLogxK

U2 - 10.1055/a-1932-6146

DO - 10.1055/a-1932-6146

M3 - Article

AN - SCOPUS:85137627909

SN - 0039-7881

VL - 55

SP - 637

EP - 646

JO - Synthesis (Germany)

JF - Synthesis (Germany)

ER -

Room Temperature, Transition-Metal-Free Arylation of Alcohols with Aryl Bromides

Abstract

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