@article{f52f995b12664b3997d9d5175a1d0ee2,
title = "Safety and immunogenicity of the 23-valent pneumococcal polysaccharide vaccine at 12 months of age, following one, two, or three doses of the 7-valent pneumococcal conjugate vaccine in infancy",
abstract = "Fijian infants aged 6 weeks were stratified by ethnicity and randomized to receive 0, 1, 2, or 3 PCV-7 doses with or without the 23-valent pneumococcal polysaccharide vaccine (PPV-23) at 12 months. Strong booster effects for all 7 PCV-7 serotypes were elicited, and for 4/7 serotypes these responses were highest in the single PCV-7 group. There were fourfold rises in GMC for all non-PCV-7 serotypes. By 17 months the PPV-23 group still had significantly higher GMC (each p < 0.001) for all serotypes. The PPV-23 was well tolerated and induced excellent responses for all serotypes which were greatest in the single PCV-7 group. � 2010 Elsevier Ltd.",
keywords = "diphtheria pertussis tetanus vaccine, Haemophilus influenzae type b vaccine, hepatitis B vaccine, hepb, Pneumococcus vaccine, unclassified drug, antibody response, article, child, clinical trial, controlled clinical trial, controlled study, diarrhea, drowsiness, drug dose comparison, drug safety, female, fever, gastroenteritis, human, immunogenicity, infection prevention, infection resistance, injection site erythema, injection site induration, injection site reaction, irritability, major clinical study, male, phase 2 clinical trial, pneumococcal infection, preschool child, priority journal, randomized controlled trial, side effect, single blind procedure, single drug dose, vaccination, vomiting, Antibodies, Bacterial, Child, Preschool, Humans, Immunization Schedule, Immunization, Secondary, Immunoglobulin G, Infant, Pneumococcal Vaccines",
author = "Fiona Russell and Paul Licciardi and Anne Balloch and Viema Biaukula and Lisi Tikoduadua and Jonathan Carapetis and Jane Nelson and Adam Jenney and Lepani Waqatakirewa and Samantha Colquhoun and Yin Cheung and Mimi Tang and MULHOLLAND, {Edward (Kim)}",
year = "2010",
language = "English",
volume = "28",
pages = "3086--3094",
journal = "Vaccine",
issn = "0264-410X",
publisher = "Elsevier",
}