Although self‐management education programs for persons with schizophrenia are being developed and advocated, uncertainty about their overall effectiveness remains. The purpose of this meta‐analysis was to examine outcomes of self‐management education interventions in persons with schizophrenia. Six electronic databases were searched. Manual searches were conducted of the reference lists of the identified studies and major psychiatric journals. Randomized controlled trials of self‐management education interventions aimed at reducing relapse and hospital readmissions, as well as improving symptoms, psychosocial functioning, and adherence to medication treatment were identified. Data were extracted and the quality of included studies were rated by two authors independently. Finally, 13 studies with 1404 patients were included. Self‐management education interventions were associated with a significant reduction of relapse events and re‐hospitalizations. Patients who received self‐management education were more likely to improve adherence to medication and symptoms compared to patients receiving other care. However, a benefit on psychosocial functioning was not confirmed in the current meta‐analysis. The study concludes that self‐management education intervention is a feasible and effective method for persons with schizophrenia and should be routinely offered to all persons with schizophrenia.