Infection with the gram-negative bacterium Burkholderia pseudomallei can result in a life-threatening disease known as melioidosis. Historically, melioidosis was a common infection in military forces serving in Southeast Asia, and it has the potential to have a serious impact on force health readiness. With the U.S. Department of Defense’s increasing strategic and operational focus across the Pacific Theater, melioidosis is an increasingly important issue from a force health protection perspective. U.S. Marines deploy annually to Darwin, Australia, a “hyperendemic” region for B. pseudomallei, to engage in training exercises. In an effort to assess the risk of B. pseudomalleiinfection to service personnel in Australia, 341 paired samples, representing pre- and post-deployment samples of Marines who trained in Australia, were analyzed for antibodies against B. pseudomallei antigens. Serological evidence of possible deployment-related infection with B. pseudomallei was found in 13 Marines. Future prospective studies are required to further characterize the risk to service members deployed to melioidosis endemic areas.
|Number of pages||10|
|Publication status||Published - Jul 2019|
Schully, K. L., Burtnick, M., Bell, M. G., Spall, A., Mayo, M., Rigas, V., Chan, A. A., Yu, K., Clark, D. V., Maves, R. C., Currie, B., Brett, P., & Lawler, J. V. (2019). Serological Evidence of Burkholderia pseudomallei Infection in U.S. Marines Who Trained in Australia From 2012–2014: A Retrospective Analysis of Archived Samples. MSMR, 26(7), 8-17.