Short Report: Reversibility of Retinal Microvascular Changes in Severe Falciparum Malaria

Richard Maude, Hugh William Fluellen Kingston, Sonia Joshi, Sanjib Mohanty, Saroj Mishra, Nicholas J White, Arjen Dondorp

Research output: Contribution to journalArticlepeer-review

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Abstract

Malarial retinopathy allows detailed study of central nervous system vascular pathology in living patients with severe malaria. An adult with cerebral malaria is described who had prominent retinal whitening with corresponding retinal microvascular obstruction, vessel dilatation, increased vascular tortuosity, and blood retinal barrier leakage with decreased visual acuity, all of which resolved on recovery. Additional study of these features and their potential role in elucidating the pathogenesis of cerebral malaria is warranted.
Original languageEnglish
Pages (from-to)493-495
Number of pages3
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume91
Issue number3
DOIs
Publication statusPublished - 3 Sept 2014

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