Soil-Transmitted Helminths in Children in a Remote Aboriginal Community in the Northern Territory: Hookworm is Rare but Strongyloides stercoralis and Trichuris trichiura Persist

Deborah Holt, Jennifer Shield, Tegan Harris, Kate Mounsey, Kieran Aland, James S. McCarthy, Bart Currie, Therese Kearns

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Abstract

    (1)  Background: soil-transmitted helminths are a problem worldwide, largely affecting disadvantaged populations. The little data available indicates high rates of infection in some remote Aboriginal communities in Australia. Studies of helminths were carried out in the same remote community in the Northern Territory in 1994–1996 and2010–2011; 

    (2)  Methods: fecal samples were collected from children aged <10 years and examined for helminths by direct smear microscopy. In the 2010–2011 study, some fecal samples were also analyzed by agar plate culture and PCR for Strongyloides stercoralis DNA. Serological analysis of finger prick dried blood spots using a S. stercoralis NIE antigen was also conducted; 

    (3)  Results and Conclusions: a reduction in fecal samples positive for S. stercoralis, hookworm and Trichuris trichiura was seen between the studies in 1994–1996and2010–2011, likely reflecting public health measures undertaken in the region to reduce intestinal helminths. Comparison of methods to detect S. stercoralis showed that PCR of fecal samples and serological testing of dried blood spots was at least as sensitive as direct smear microscopy and agar plate culture. These methods have advantages for use in remote field studies.


    Original languageEnglish
    Title of host publicationNeglected and Emerging Tropical Diseases in South and Southeast Asia and Northern Australia
    EditorsPatricia Graves, Thewarach Laha, Peter A. Leggat, Khin Saw Aye
    Place of PublicationBasel, Switzerland
    PublisherMDPI AG
    Pages104-112
    Number of pages9
    ISBN (Electronic)978-3-03897-089-3
    ISBN (Print)978-3-03897-090-7
    DOIs
    Publication statusPublished - 2018

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