Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections

M Edwards, Peter Fagan, Heidi Smith-Vaughan, Bart Currie, K Sriprakash

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Epidemiologically unrelated Streptococcus pyogenes strains isolated from blood, throat, and skin were assayed for adherence to HEp2 and HaCaT cells. Invasive isolates showed significantly higher avidity for these cell lines than isolates from skin and throat. In general, S. pyogenes showed greater binding to HaCaT cells than to HEp2 cells.
Original languageEnglish
Pages (from-to)3936-3938
Number of pages3
JournalJournal of Clinical Microbiology
Volume41
Issue number8
Publication statusPublished - 2003

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Streptococcus pyogenes
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Edwards, M ; Fagan, Peter ; Smith-Vaughan, Heidi ; Currie, Bart ; Sriprakash, K. / Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections. In: Journal of Clinical Microbiology. 2003 ; Vol. 41, No. 8. pp. 3936-3938.
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abstract = "Epidemiologically unrelated Streptococcus pyogenes strains isolated from blood, throat, and skin were assayed for adherence to HEp2 and HaCaT cells. Invasive isolates showed significantly higher avidity for these cell lines than isolates from skin and throat. In general, S. pyogenes showed greater binding to HaCaT cells than to HEp2 cells.",
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Edwards, M, Fagan, P, Smith-Vaughan, H, Currie, B & Sriprakash, K 2003, 'Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections', Journal of Clinical Microbiology, vol. 41, no. 8, pp. 3936-3938.

Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections. / Edwards, M; Fagan, Peter; Smith-Vaughan, Heidi; Currie, Bart; Sriprakash, K.

In: Journal of Clinical Microbiology, Vol. 41, No. 8, 2003, p. 3936-3938.

Research output: Contribution to journal › Article › Research › peer-review

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AU - Edwards, M

AU - Fagan, Peter

AU - Smith-Vaughan, Heidi

AU - Currie, Bart

AU - Sriprakash, K

PY - 2003

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Edwards M, Fagan P, Smith-Vaughan H, Currie B, Sriprakash K. Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections. Journal of Clinical Microbiology. 2003;41(8):3936-3938.