Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections

M Edwards, Peter Fagan, Heidi Smith-Vaughan, Bart Currie, K Sriprakash

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    Epidemiologically unrelated Streptococcus pyogenes strains isolated from blood, throat, and skin were assayed for adherence to HEp2 and HaCaT cells. Invasive isolates showed significantly higher avidity for these cell lines than isolates from skin and throat. In general, S. pyogenes showed greater binding to HaCaT cells than to HEp2 cells.
    Original languageEnglish
    Pages (from-to)3936-3938
    Number of pages3
    JournalJournal of Clinical Microbiology
    Issue number8
    Publication statusPublished - 2003


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