Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections

M Edwards, Peter Fagan, Heidi Smith-Vaughan, Bart Currie, K Sriprakash

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Epidemiologically unrelated Streptococcus pyogenes strains isolated from blood, throat, and skin were assayed for adherence to HEp2 and HaCaT cells. Invasive isolates showed significantly higher avidity for these cell lines than isolates from skin and throat. In general, S. pyogenes showed greater binding to HaCaT cells than to HEp2 cells.
Original languageEnglish
Pages (from-to)3936-3938
Number of pages3
JournalJournal of Clinical Microbiology
Volume41
Issue number8
Publication statusPublished - 2003

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Streptococcus pyogenes
Pharynx
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Skin
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title = "Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections",
abstract = "Epidemiologically unrelated Streptococcus pyogenes strains isolated from blood, throat, and skin were assayed for adherence to HEp2 and HaCaT cells. Invasive isolates showed significantly higher avidity for these cell lines than isolates from skin and throat. In general, S. pyogenes showed greater binding to HaCaT cells than to HEp2 cells.",
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author = "M Edwards and Peter Fagan and Heidi Smith-Vaughan and Bart Currie and K Sriprakash",
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Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections. / Edwards, M; Fagan, Peter; Smith-Vaughan, Heidi; Currie, Bart; Sriprakash, K.

In: Journal of Clinical Microbiology, Vol. 41, No. 8, 2003, p. 3936-3938.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections

AU - Edwards, M

AU - Fagan, Peter

AU - Smith-Vaughan, Heidi

AU - Currie, Bart

AU - Sriprakash, K

PY - 2003

Y1 - 2003

N2 - Epidemiologically unrelated Streptococcus pyogenes strains isolated from blood, throat, and skin were assayed for adherence to HEp2 and HaCaT cells. Invasive isolates showed significantly higher avidity for these cell lines than isolates from skin and throat. In general, S. pyogenes showed greater binding to HaCaT cells than to HEp2 cells.

AB - Epidemiologically unrelated Streptococcus pyogenes strains isolated from blood, throat, and skin were assayed for adherence to HEp2 and HaCaT cells. Invasive isolates showed significantly higher avidity for these cell lines than isolates from skin and throat. In general, S. pyogenes showed greater binding to HaCaT cells than to HEp2 cells.

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KW - epidemiological data

KW - HEp 2 cell

KW - human

KW - human cell

KW - major clinical study

KW - pathogenicity

KW - priority journal

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KW - Streptococcus infection

KW - Streptococcus pyogenes

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