Surface Analyses and Immune Reactivities of Major Cell Wall-Associated Proteins of Group A Streptococcus

J Cole, R Ramirez, Bart Currie, S Cordwell, S Djordjevic, M Walker

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A proteomic analysis was undertaken to identify cell wall-associated proteins of Streptococcus pyogenes. Seventy-four distinct cell wall-associated proteins were identified, 66 of which were novel. Thirty-three proteins were immunoreactive with pooled S. pyogenes-reactive human antisera. Biotinylation of the GAS cell surface identified 23 cell wall-associated proteins that are surface exposed. Copyright � 2005, American Society for Microbiology. All Rights Reserved.
    Original languageEnglish
    Pages (from-to)3137-3146
    Number of pages10
    JournalInfection and Immunity
    Volume73
    Issue number5
    Publication statusPublished - 2005

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