Synthesis of ammonium substituted β-cyclodextrins for enantioseparation of anionic analytes

I. Wayan Muderawan, Teng Teng Ong, Wei Hua Tang, David J. Young, Chi Bun Ching, Siu Choon Ng

Research output: Contribution to journalArticle

Abstract

New ammonium functionalized cyclodextrins can be prepared in excellent yields by displacement of 6-tosyl-β-cyclodextrin with alkylimidazoles, pyridine or alkylamines and achieve excellent enantioseparation of dansyl amino acids presumably due to electrostatic interactions between the cationic host and anionic guest.

Original languageEnglish
Pages (from-to)1747-1749
Number of pages3
JournalTetrahedron Letters
Volume46
Issue number10
DOIs
Publication statusPublished - 7 Mar 2005
Externally publishedYes

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