Thyroid nodules in children and adolescents: Investigation and management

Jessica L. Sandy, Angela Titmuss, Shihab Hameed, Yoon Hi Cho, Gideon Sandler, Paul Benitez-Aguirre

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)
123 Downloads (Pure)


Clinically detectable thyroid nodules are less common in children than adults. However, they are associated with an increased risk of malignancy. Therefore, thorough evaluation of paediatric thyroid nodules is necessary, and an understanding of the features associated with a higher risk of malignancy is important to guide management and referral. Thyroid cancer in children differs significantly from that seen in adults in terms of genetics, presentation, response to treatment and prognosis. Children often present with more advanced disease, but the vast majority have excellent long-term prognosis. Evaluation and management of thyroid nodules and thyroid cancer require a multidisciplinary team approach and involvement of specialists with experience in this field. This review summarises investigative pathways for thyroid nodules in children and outlines current management strategies for paediatric thyroid nodules and cancer.

Original languageEnglish
Pages (from-to)2163-2168
Number of pages6
JournalJournal of Paediatrics and Child Health
Issue number12
Publication statusPublished - Dec 2022

Bibliographical note

Funding Information:
Open access publishing facilitated by The University of Sydney, as part of the Wiley - The University of Sydney agreement via the Council of Australian University Librarians.

Publisher Copyright:
© 2022 The Authors. Journal of Paediatrics and Child Health published by John Wiley & Sons Australia, Ltd on behalf of Paediatrics and Child Health Division (The Royal Australasian College of Physicians).


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