Toward the prevention of coronavirus infection: what role can polymers play?

X. Jiang, Z. Li, D. J. Young, M. Liu, C. Wu, Y. L. Wu, X. J. Loh

Research output: Contribution to journalReview articlepeer-review

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Abstract

Severe acute respiratory syndrome–associated coronavirus 2 has caused a global public health crisis with high rates of infection and mortality. Treatment and prevention approaches include vaccine development, the design of small-molecule antiviral drugs, and macromolecular neutralizing antibodies. Polymers have been designed for effective virus inhibition and as antiviral drug delivery carriers. This review summarizes recent progress and provides a perspective on polymer-based approaches for the treatment and prevention of coronavirus infection. These polymer-based partners include polyanion/polycations, dendritic polymers, macromolecular prodrugs, and polymeric drug delivery systems that have the potential to significantly improve the efficacy of antiviral therapeutics.

Original languageEnglish
Article number100140
Pages (from-to)1-11
Number of pages11
JournalMaterials Today Advances
Volume10
Early online date20 Mar 2021
DOIs
Publication statusPublished - Jun 2021

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