Trajectories of quality of life, life satisfaction, and psychological adjustment after prostate cancer

Suzanne K. Chambers, Shu Kay Ng, Peter Baade, Joanne F. Aitken, Melissa K. Hyde, Gary Wittert, Mark Frydenberg, Jeff Dunn

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    Background: To describe trajectories of health-related quality of life (QoL), life satisfaction, and psychological adjustment for men with prostate cancer over the medium to long term and identify predictors of poorer outcomes using growth mixture models. 

    Methods: One-thousand sixty-four (82.4% response) men diagnosed with prostate cancer were recruited close to diagnosis and assessed over a 72-month (6-year) period with self-report assessment of health-related QoL, life satisfaction, cancer-related distress, and prostate specific antigen anxiety. Urinary, bowel, and sexual function were also assessed using validated questionnaires. 

    Results: Poorer physical QOL was predicted by older age, lower education, lower income, comorbidities, and receiving hormone therapy. Lower life satisfaction was related to younger age, lower income, not being partnered, and comorbidities. Poorer psychological trajectories were predicted by younger age, lower income, comorbidities, and receiving radical prostatectomy or brachytherapy. Better urinary, bowel, and sexual function were related to better global outcomes over time. Anxiety about prostate specific antigen testing was rare. 

    Conclusions: Distinct trajectories exist for medium- to long-term QoL, life satisfaction, and psychological adjustment after prostate cancer; with age and socioeconomic deprivation playing a differential role in men's survivorship profile and the impact of functional status on outcomes increasing over time. These results reinforce the need for an appraisal of men's life course in addition to treatment side effects when planning survivorship care after cancer.

    Original languageEnglish
    Pages (from-to)1576-1585
    Number of pages10
    JournalPsycho-Oncology
    Volume26
    Issue number10
    DOIs
    Publication statusPublished - Oct 2017

    Fingerprint

    Prostatic Neoplasms
    Quality of Life
    Comorbidity
    Prostate-Specific Antigen
    Survival Rate
    Anxiety
    Brachytherapy
    Prostatectomy
    Self Report
    Neoplasms
    Emotional Adjustment
    Hormones
    Psychology
    Education
    Therapeutics
    Growth

    Cite this

    Chambers, S. K., Ng, S. K., Baade, P., Aitken, J. F., Hyde, M. K., Wittert, G., ... Dunn, J. (2017). Trajectories of quality of life, life satisfaction, and psychological adjustment after prostate cancer. Psycho-Oncology, 26(10), 1576-1585. https://doi.org/10.1002/pon.4342
    Chambers, Suzanne K. ; Ng, Shu Kay ; Baade, Peter ; Aitken, Joanne F. ; Hyde, Melissa K. ; Wittert, Gary ; Frydenberg, Mark ; Dunn, Jeff. / Trajectories of quality of life, life satisfaction, and psychological adjustment after prostate cancer. In: Psycho-Oncology. 2017 ; Vol. 26, No. 10. pp. 1576-1585.
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    abstract = "Background: To describe trajectories of health-related quality of life (QoL), life satisfaction, and psychological adjustment for men with prostate cancer over the medium to long term and identify predictors of poorer outcomes using growth mixture models. Methods: One-thousand sixty-four (82.4{\%} response) men diagnosed with prostate cancer were recruited close to diagnosis and assessed over a 72-month (6-year) period with self-report assessment of health-related QoL, life satisfaction, cancer-related distress, and prostate specific antigen anxiety. Urinary, bowel, and sexual function were also assessed using validated questionnaires. Results: Poorer physical QOL was predicted by older age, lower education, lower income, comorbidities, and receiving hormone therapy. Lower life satisfaction was related to younger age, lower income, not being partnered, and comorbidities. Poorer psychological trajectories were predicted by younger age, lower income, comorbidities, and receiving radical prostatectomy or brachytherapy. Better urinary, bowel, and sexual function were related to better global outcomes over time. Anxiety about prostate specific antigen testing was rare. Conclusions: Distinct trajectories exist for medium- to long-term QoL, life satisfaction, and psychological adjustment after prostate cancer; with age and socioeconomic deprivation playing a differential role in men's survivorship profile and the impact of functional status on outcomes increasing over time. These results reinforce the need for an appraisal of men's life course in addition to treatment side effects when planning survivorship care after cancer.",
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    Chambers, SK, Ng, SK, Baade, P, Aitken, JF, Hyde, MK, Wittert, G, Frydenberg, M & Dunn, J 2017, 'Trajectories of quality of life, life satisfaction, and psychological adjustment after prostate cancer', Psycho-Oncology, vol. 26, no. 10, pp. 1576-1585. https://doi.org/10.1002/pon.4342

    Trajectories of quality of life, life satisfaction, and psychological adjustment after prostate cancer. / Chambers, Suzanne K.; Ng, Shu Kay; Baade, Peter; Aitken, Joanne F.; Hyde, Melissa K.; Wittert, Gary; Frydenberg, Mark; Dunn, Jeff.

    In: Psycho-Oncology, Vol. 26, No. 10, 10.2017, p. 1576-1585.

    Research output: Contribution to journalArticleResearchpeer-review

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    T1 - Trajectories of quality of life, life satisfaction, and psychological adjustment after prostate cancer

    AU - Chambers, Suzanne K.

    AU - Ng, Shu Kay

    AU - Baade, Peter

    AU - Aitken, Joanne F.

    AU - Hyde, Melissa K.

    AU - Wittert, Gary

    AU - Frydenberg, Mark

    AU - Dunn, Jeff

    PY - 2017/10

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    N2 - Background: To describe trajectories of health-related quality of life (QoL), life satisfaction, and psychological adjustment for men with prostate cancer over the medium to long term and identify predictors of poorer outcomes using growth mixture models. Methods: One-thousand sixty-four (82.4% response) men diagnosed with prostate cancer were recruited close to diagnosis and assessed over a 72-month (6-year) period with self-report assessment of health-related QoL, life satisfaction, cancer-related distress, and prostate specific antigen anxiety. Urinary, bowel, and sexual function were also assessed using validated questionnaires. Results: Poorer physical QOL was predicted by older age, lower education, lower income, comorbidities, and receiving hormone therapy. Lower life satisfaction was related to younger age, lower income, not being partnered, and comorbidities. Poorer psychological trajectories were predicted by younger age, lower income, comorbidities, and receiving radical prostatectomy or brachytherapy. Better urinary, bowel, and sexual function were related to better global outcomes over time. Anxiety about prostate specific antigen testing was rare. Conclusions: Distinct trajectories exist for medium- to long-term QoL, life satisfaction, and psychological adjustment after prostate cancer; with age and socioeconomic deprivation playing a differential role in men's survivorship profile and the impact of functional status on outcomes increasing over time. These results reinforce the need for an appraisal of men's life course in addition to treatment side effects when planning survivorship care after cancer.

    AB - Background: To describe trajectories of health-related quality of life (QoL), life satisfaction, and psychological adjustment for men with prostate cancer over the medium to long term and identify predictors of poorer outcomes using growth mixture models. Methods: One-thousand sixty-four (82.4% response) men diagnosed with prostate cancer were recruited close to diagnosis and assessed over a 72-month (6-year) period with self-report assessment of health-related QoL, life satisfaction, cancer-related distress, and prostate specific antigen anxiety. Urinary, bowel, and sexual function were also assessed using validated questionnaires. Results: Poorer physical QOL was predicted by older age, lower education, lower income, comorbidities, and receiving hormone therapy. Lower life satisfaction was related to younger age, lower income, not being partnered, and comorbidities. Poorer psychological trajectories were predicted by younger age, lower income, comorbidities, and receiving radical prostatectomy or brachytherapy. Better urinary, bowel, and sexual function were related to better global outcomes over time. Anxiety about prostate specific antigen testing was rare. Conclusions: Distinct trajectories exist for medium- to long-term QoL, life satisfaction, and psychological adjustment after prostate cancer; with age and socioeconomic deprivation playing a differential role in men's survivorship profile and the impact of functional status on outcomes increasing over time. These results reinforce the need for an appraisal of men's life course in addition to treatment side effects when planning survivorship care after cancer.

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    KW - longitudinal

    KW - oncology

    KW - prostate

    KW - psychological distress

    KW - quality of life

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    DO - 10.1002/pon.4342

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