We conducted a pilot randomized controlled trial comparing trimethoprim-sulfamethoxazole to benzathine penicillin for treatment of impetigo in Aboriginal children. Treatment was successful in 7 of 7 children treated with trimethoprim-sulfamethoxazole and 5 of 6 treated with benzathine penicillin. Trimethoprim-sulfamethoxazole achieved microbiological clearance and healing of sores from which ?-hemolytic streptococci and community-associated methicillin-resistant Staphylococcus aureus were initially cultured. � 2010 Paediatrics and Child Health Division (Royal Australasian College of Physicians).
Tong, S., Andrews, R., Kearns, T., Gundjirryirr, R., McDonald, M., Currie, B., & Carapetis, J. (2010). Trimethopim-sulfamethoxazole compared with benzathine penicillin for treatment of impetigo in Aboriginal children: A pilot randomised controlled trial: Case report. Journal of Paediatrics and Child Health, 46(3), 131-133. https://doi.org/10.1111/j.1440-1754.2010.01697.x