Tuberculosis (TB)

Craig Steven Boutlis

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Mycobacterium tuberculosis (MTB) is a bacterium which is estimated to currently infect over one third of the world’s six billion people, causing over eight million new cases of disease annually.1 Infection is much less common in populations with good access to health care and where overcrowded living conditions are uncommon. Most people infected with MTB will never realise it, as the immunity they develop contains the infection, but around 10–20% will at some stage become sick with active TB, a serious but curable disease.2 Pulmonary TB is by far the most frequent presentation of disease and is the form primarily involved in the transmission of infection. Extra-pulmonary TB is rarely infectious and may affect the linings of the lungs or heart (causing pleural effusions or pericarditis), lymph nodes, bone and joints, genitourinary tract, brain (causing meningitis or space-occupying lesions), peritoneum or any other part of the body. All forms of active TB may present with systemic symptoms including fevers, weight loss, night sweats, and loss of appetite.
Original languageEnglish
Title of host publicationCARPA Standard Treatment Manual Reference Book
EditorsD Ewald
Place of PublicationAlice Springs
PublisherCentral Australian Rural Practitioners Association
ISBN (Print)0646429590
Publication statusPublished - 2004


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