Type 2 diabetes after a pregnancy with gestational diabetes among First Nations women in Australia: The PANDORA study

Anna J. Wood; Jacqueline A. Boyle; Elizabeth L.M. Barr; Federica Barzi; Matthew J.L. Hare; Angela Titmuss; Danielle K. Longmore; Elizabeth Death; Joanna Kelaart; Marie Kirkwood; Sian Graham; Christine Connors; Elizabeth Moore; Kerin O'Dea; Jeremy J.N. Oats; Harold D. McIntyre; Paul Z. Zimmet; Zhong X. Lu; Alex Brown; Jonathan E. Shaw; Louise J. Maple-Brown

doi:10.1016/j.diabres.2021.109092

Type 2 diabetes after a pregnancy with gestational diabetes among First Nations women in Australia: The PANDORA study

Anna J. Wood, Jacqueline A. Boyle, Elizabeth L.M. Barr, Federica Barzi, Matthew J.L. Hare, Angela Titmuss, Danielle K. Longmore, Elizabeth Death, Joanna Kelaart, Marie Kirkwood, Sian Graham, Christine Connors, Elizabeth Moore, Kerin O'Dea, Jeremy J.N. Oats, Harold D. McIntyre, Paul Z. Zimmet, Zhong X. Lu, Alex Brown, Jonathan E. ShawLouise J. Maple-Brown

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

116 Downloads (Pure)

Abstract

Aims: To determine among First Nations and Europid pregnant women the cumulative incidence and predictors of postpartum type 2 diabetes and prediabetes and describe postpartum cardiovascular disease (CVD) risk profiles.

Methods: PANDORA is a prospective longitudinal cohort of women recruited in pregnancy. Ethnic-specific rates of postpartum type 2 diabetes and prediabetes were reported for women with diabetes in pregnancy (DIP), gestational diabetes (GDM) or normoglycaemia in pregnancy over a short follow-up of 2.5 years (n = 325). Pregnancy characteristics and CVD risk profiles according to glycaemic status, and factors associated with postpartum diabetes/prediabetes were examined in First Nations women.

Results: The cumulative incidence of postpartum type 2 diabetes among women with DIP or GDM were higher for First Nations women (48%, 13/27, women with DIP, 13%, 11/82, GDM), compared to Europid women (nil DIP or GDM p < 0.001). Characteristics associated with type 2 diabetes/prediabetes among First Nations women with GDM/DIP included, older age, multiparity, family history of diabetes, higher glucose values, insulin use and body mass index (BMI).

Conclusions: First Nations women experience a high incidence of postpartum type 2 diabetes after GDM/DIP, highlighting the need for culturally responsive policies at an individual and systems level, to prevent diabetes and its complications.

Original language	English
Article number	109092
Pages (from-to)	1-10
Number of pages	10
Journal	Diabetes Research and Clinical Practice
Volume	181
DOIs	https://doi.org/10.1016/j.diabres.2021.109092
Publication status	Published - Nov 2021

Bibliographical note

Publisher Copyright:
© 2021 The Author(s)

Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1016/j.diabres.2021.109092

47261875-oaFinal published version, 913 KBLicence: CC BY-NC-ND

Cite this

Wood, A. J., Boyle, J. A., Barr, E. L. M., Barzi, F., Hare, M. J. L., Titmuss, A., Longmore, D. K., Death, E., Kelaart, J., Kirkwood, M., Graham, S., Connors, C., Moore, E., O'Dea, K., Oats, J. J. N., McIntyre, H. D., Zimmet, P. Z., Lu, Z. X., Brown, A., ... Maple-Brown, L. J. (2021). Type 2 diabetes after a pregnancy with gestational diabetes among First Nations women in Australia: The PANDORA study. Diabetes Research and Clinical Practice, 181, 1-10. Article 109092. https://doi.org/10.1016/j.diabres.2021.109092

@article{999ad777e3c0406ea3e8885bb6f06873,

title = "Type 2 diabetes after a pregnancy with gestational diabetes among First Nations women in Australia: The PANDORA study",

abstract = "Aims: To determine among First Nations and Europid pregnant women the cumulative incidence and predictors of postpartum type 2 diabetes and prediabetes and describe postpartum cardiovascular disease (CVD) risk profiles. Methods: PANDORA is a prospective longitudinal cohort of women recruited in pregnancy. Ethnic-specific rates of postpartum type 2 diabetes and prediabetes were reported for women with diabetes in pregnancy (DIP), gestational diabetes (GDM) or normoglycaemia in pregnancy over a short follow-up of 2.5 years (n = 325). Pregnancy characteristics and CVD risk profiles according to glycaemic status, and factors associated with postpartum diabetes/prediabetes were examined in First Nations women. Results: The cumulative incidence of postpartum type 2 diabetes among women with DIP or GDM were higher for First Nations women (48\%, 13/27, women with DIP, 13\%, 11/82, GDM), compared to Europid women (nil DIP or GDM p < 0.001). Characteristics associated with type 2 diabetes/prediabetes among First Nations women with GDM/DIP included, older age, multiparity, family history of diabetes, higher glucose values, insulin use and body mass index (BMI). Conclusions: First Nations women experience a high incidence of postpartum type 2 diabetes after GDM/DIP, highlighting the need for culturally responsive policies at an individual and systems level, to prevent diabetes and its complications.",

keywords = "Diabetes in pregnancy, Gestational diabetes, Indigenous health",

author = "Wood, \{Anna J.\} and Boyle, \{Jacqueline A.\} and Barr, \{Elizabeth L.M.\} and Federica Barzi and Hare, \{Matthew J.L.\} and Angela Titmuss and Longmore, \{Danielle K.\} and Elizabeth Death and Joanna Kelaart and Marie Kirkwood and Sian Graham and Christine Connors and Elizabeth Moore and Kerin O'Dea and Oats, \{Jeremy J.N.\} and McIntyre, \{Harold D.\} and Zimmet, \{Paul Z.\} and Lu, \{Zhong X.\} and Alex Brown and Shaw, \{Jonathan E.\} and Maple-Brown, \{Louise J.\}",

year = "2021",

month = nov,

doi = "10.1016/j.diabres.2021.109092",

language = "English",

volume = "181",

pages = "1--10",

journal = "Diabetes Research and Clinical Practice",

issn = "0168-8227",

publisher = "Elsevier Ireland Ltd",

}

Wood, AJ, Boyle, JA, Barr, ELM, Barzi, F, Hare, MJL , Titmuss, A, Longmore, DK, Death, E, Kelaart, J, Kirkwood, M, Graham, S, Connors, C, Moore, E, O'Dea, K, Oats, JJN, McIntyre, HD, Zimmet, PZ, Lu, ZX, Brown, A, Shaw, JE & Maple-Brown, LJ 2021, 'Type 2 diabetes after a pregnancy with gestational diabetes among First Nations women in Australia: The PANDORA study', Diabetes Research and Clinical Practice, vol. 181, 109092, pp. 1-10. https://doi.org/10.1016/j.diabres.2021.109092

TY - JOUR

T1 - Type 2 diabetes after a pregnancy with gestational diabetes among First Nations women in Australia

T2 - The PANDORA study

AU - Wood, Anna J.

AU - Boyle, Jacqueline A.

AU - Barr, Elizabeth L.M.

AU - Barzi, Federica

AU - Hare, Matthew J.L.

AU - Titmuss, Angela

AU - Longmore, Danielle K.

AU - Death, Elizabeth

AU - Kelaart, Joanna

AU - Kirkwood, Marie

AU - Graham, Sian

AU - Connors, Christine

AU - Moore, Elizabeth

AU - O'Dea, Kerin

AU - Oats, Jeremy J.N.

AU - McIntyre, Harold D.

AU - Zimmet, Paul Z.

AU - Lu, Zhong X.

AU - Brown, Alex

AU - Shaw, Jonathan E.

AU - Maple-Brown, Louise J.

PY - 2021/11

Y1 - 2021/11

N2 - Aims: To determine among First Nations and Europid pregnant women the cumulative incidence and predictors of postpartum type 2 diabetes and prediabetes and describe postpartum cardiovascular disease (CVD) risk profiles. Methods: PANDORA is a prospective longitudinal cohort of women recruited in pregnancy. Ethnic-specific rates of postpartum type 2 diabetes and prediabetes were reported for women with diabetes in pregnancy (DIP), gestational diabetes (GDM) or normoglycaemia in pregnancy over a short follow-up of 2.5 years (n = 325). Pregnancy characteristics and CVD risk profiles according to glycaemic status, and factors associated with postpartum diabetes/prediabetes were examined in First Nations women. Results: The cumulative incidence of postpartum type 2 diabetes among women with DIP or GDM were higher for First Nations women (48%, 13/27, women with DIP, 13%, 11/82, GDM), compared to Europid women (nil DIP or GDM p < 0.001). Characteristics associated with type 2 diabetes/prediabetes among First Nations women with GDM/DIP included, older age, multiparity, family history of diabetes, higher glucose values, insulin use and body mass index (BMI). Conclusions: First Nations women experience a high incidence of postpartum type 2 diabetes after GDM/DIP, highlighting the need for culturally responsive policies at an individual and systems level, to prevent diabetes and its complications.

AB - Aims: To determine among First Nations and Europid pregnant women the cumulative incidence and predictors of postpartum type 2 diabetes and prediabetes and describe postpartum cardiovascular disease (CVD) risk profiles. Methods: PANDORA is a prospective longitudinal cohort of women recruited in pregnancy. Ethnic-specific rates of postpartum type 2 diabetes and prediabetes were reported for women with diabetes in pregnancy (DIP), gestational diabetes (GDM) or normoglycaemia in pregnancy over a short follow-up of 2.5 years (n = 325). Pregnancy characteristics and CVD risk profiles according to glycaemic status, and factors associated with postpartum diabetes/prediabetes were examined in First Nations women. Results: The cumulative incidence of postpartum type 2 diabetes among women with DIP or GDM were higher for First Nations women (48%, 13/27, women with DIP, 13%, 11/82, GDM), compared to Europid women (nil DIP or GDM p < 0.001). Characteristics associated with type 2 diabetes/prediabetes among First Nations women with GDM/DIP included, older age, multiparity, family history of diabetes, higher glucose values, insulin use and body mass index (BMI). Conclusions: First Nations women experience a high incidence of postpartum type 2 diabetes after GDM/DIP, highlighting the need for culturally responsive policies at an individual and systems level, to prevent diabetes and its complications.

KW - Diabetes in pregnancy

KW - Gestational diabetes

KW - Indigenous health

UR - https://www.scopus.com/pages/publications/85118188614

U2 - 10.1016/j.diabres.2021.109092

DO - 10.1016/j.diabres.2021.109092

M3 - Article

C2 - 34653565

AN - SCOPUS:85118188614

SN - 0168-8227

VL - 181

SP - 1

EP - 10

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

M1 - 109092

ER -

Type 2 diabetes after a pregnancy with gestational diabetes among First Nations women in Australia: The PANDORA study

Abstract

Bibliographical note

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this