Using Genomics to Understand the Epidemiology of Infectious Diseases in the Northern Territory of Australia

Ella M. Meumann, Vicki L. Krause, Robert Baird, Bart J. Currie

Research output: Contribution to journalReview articlepeer-review

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Abstract

The Northern Territory (NT) is a geographically remote region of northern and central Australia. Approximately a third of the population are First Nations Australians, many of whom live in remote regions. Due to the physical environment and climate, and scale of social inequity, the rates of many infectious diseases are the highest nationally. Molecular typing and genomic sequencing in research and public health have provided considerable new knowledge on the epidemiology of infectious diseases in the NT. We review the applications of genomic sequencing technology for molecular typing, identification of transmission clusters, phylogenomics, antimicrobial resistance prediction, and pathogen detection. We provide examples where these methodologies have been applied to infectious diseases in the NT and discuss the next steps in public health implementation of this technology.

Original languageEnglish
Article number181
Pages (from-to)1-17
Number of pages17
JournalTropical Medicine and Infectious Disease
Volume7
Issue number8
DOIs
Publication statusPublished - Aug 2022

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