@article{b98a33e31d9946929ac686761e080f53,
title = "Vancomycin Exposure and Acute Kidney Injury Outcome: A Snapshot from the CAMERA2 Study",
abstract = "Among patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia from a prospective randomized clinical trial, acute kidney injury (AKI) rates increased with increasing vancomycin exposure, even within the therapeutic range. AKI was independently more common for the (flu)cloxacillin group. Day 2 vancomycin AUC ≥470 mg·h/L was significantly associated with AKI, independent of (flu)cloxacillin receipt. ",
keywords = "acute kidney injury, AUC, combination therapy, MRSA bacteremia, nephrotoxicity, pharmacokinetics, toxicodynamics, vancomycin, β-lactam",
author = "{CAMERA2 Study Group} and Jiajun Liu and Tong, {Steven Y.C.} and Davis, {Joshua S.} and Rhodes, {Nathaniel J.} and Scheetz, {Marc H.} and Anna Ralph",
note = "Publisher Copyright: {\textcopyright} 2020 The Author(s). Published by Oxford University Press on behalf of Infectious Diseases Society of America. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2020",
month = dec,
doi = "10.1093/ofid/ofaa538",
language = "English",
volume = "7",
pages = "1--5",
journal = "Open Forum Infectious Diseases",
issn = "2328-8957",
publisher = "Oxford University Press",
number = "12",
}