Vancomycin Exposure and Acute Kidney Injury Outcome: A Snapshot from the CAMERA2 Study

Jiajun Liu, Steven Y.C. Tong, Joshua S. Davis, Nathaniel J. Rhodes, Marc H. Scheetz

Research output: Contribution to journalArticlepeer-review

Abstract

Among patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia from a prospective randomized clinical trial, acute kidney injury (AKI) rates increased with increasing vancomycin exposure, even within the therapeutic range. AKI was independently more common for the (flu)cloxacillin group. Day 2 vancomycin AUC ≥470 mg·h/L was significantly associated with AKI, independent of (flu)cloxacillin receipt.

Original languageEnglish
Article numberofaa538
Pages (from-to)1-5
Number of pages5
JournalOpen Forum Infectious Diseases
Volume7
Issue number12
Early online dateNov 2020
DOIs
Publication statusPublished - Dec 2020

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