WCN26-2082 EPIDEMIOLOGICAL PROFILE OF HOSPITALIZATIONS DUE TO TUBULOINTERSTITIAL KIDNEY DISEASES IN BRAZIL: ANALYSIS BY GENDER AND REGION (2015–2025)

Davi Acselrad; Gabriel Parente; Marcelo Filho; Tiago Maia; Isis Holanda; Elizabeth Daher; Polianna Albuquerque; Erick Mota; Priscila Wenyan; Andre Mota; Geraldo Silva Junior

doi:10.1016/j.ekir.2026.105799

WCN26-2082 EPIDEMIOLOGICAL PROFILE OF HOSPITALIZATIONS DUE TO TUBULOINTERSTITIAL KIDNEY DISEASES IN BRAZIL: ANALYSIS BY GENDER AND REGION (2015–2025)

Davi Acselrad, Gabriel Parente, Marcelo Filho, Tiago Maia, Isis Holanda, Elizabeth Daher, Polianna Albuquerque, Erick Mota, Priscila Wenyan, Andre Mota, Geraldo Silva Junior

Biomedical Sciences

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper published in Proceedings › peer-review

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Abstract

Introduction
Tubulointerstitial kidney diseases (TKD) comprise a group of disorders with similar patterns of tubular and interstitial injury, commonly caused by excessive exposure to toxins, drugs, or infections. The main categories include acute tubular necrosis and acute or chronic tubulointerstitial nephritis, the latter accounting for about 20% of acute kidney injury (AKI) cases. This study aimed to analyze the epidemiological profile of hospitalizations for tubulointerstitial kidney diseases in Brazil from 2015 to 2025.

Methods
This was a cross-sectional, documentary, and quantitative study using data from the Department of Informatics of the Unified Health System (DATASUS) on hospital admissions for tubulointerstitial kidney diseases in each Brazilian region between 2015 and 2025, with emphasis on gender distribution.

Results
A total of 660,555 hospitalizations for tubulointerstitial kidney diseases were recorded nationwide. Females accounted for 67.9% (n=448,545) and males for 32.1% (n=212,010). By region, the Southeast had the highest number of admissions: 32.3% (n=212,968), followed by the Northeast 25.7% (n=169,641), South 22.4% (n=147,911), North (11%; n=72,608), and Center-West 8.7% (n=57,427).

Conclusion
This study revealed the regional distribution of hospitalizations for tubulointerstitial kidney diseases in Brazil, highlighting a predominance in the Southeast region and among females. The higher concentration in the most populous region suggests that sociodemographic factors may influence both diagnosis and access to treatment. Moreover, the predominance of hospitalizations among women may be explained by greater healthcare-seeking behavior, a higher prevalence of autoimmune diseases, and hormonal factors that predispose to urinary tract and renal disorders.

Original language	English
Title of host publication	ISN World Congress of Nephrology (WCN) 2026 Abstracts
Place of Publication	Kidney International Reports
Publisher	Elsevier
Pages	1-1
Number of pages	1
Volume	11
Edition	1
DOIs	https://doi.org/10.1016/j.ekir.2026.105799
Publication status	Published - Mar 2026

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 10 Reduced Inequalities

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142982270-oaFinal published version, 130 KBLicence: CC BY-NC-ND

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Acselrad, D., Parente, G., Filho, M., Maia, T., Holanda, I., Daher, E., Albuquerque, P., Mota, E., Wenyan, P., Mota, A., & Silva Junior, G. (2026). WCN26-2082 EPIDEMIOLOGICAL PROFILE OF HOSPITALIZATIONS DUE TO TUBULOINTERSTITIAL KIDNEY DISEASES IN BRAZIL: ANALYSIS BY GENDER AND REGION (2015–2025). In ISN World Congress of Nephrology (WCN) 2026 Abstracts (1 ed., Vol. 11, pp. 1-1). Article 105799 Elsevier. https://doi.org/10.1016/j.ekir.2026.105799

@inproceedings{60e06acf438b4ffdb8c1c181f4b51667,

title = "WCN26-2082 EPIDEMIOLOGICAL PROFILE OF HOSPITALIZATIONS DUE TO TUBULOINTERSTITIAL KIDNEY DISEASES IN BRAZIL: ANALYSIS BY GENDER AND REGION (2015–2025)",

abstract = "Introduction Tubulointerstitial kidney diseases (TKD) comprise a group of disorders with similar patterns of tubular and interstitial injury, commonly caused by excessive exposure to toxins, drugs, or infections. The main categories include acute tubular necrosis and acute or chronic tubulointerstitial nephritis, the latter accounting for about 20\% of acute kidney injury (AKI) cases. This study aimed to analyze the epidemiological profile of hospitalizations for tubulointerstitial kidney diseases in Brazil from 2015 to 2025. Methods This was a cross-sectional, documentary, and quantitative study using data from the Department of Informatics of the Unified Health System (DATASUS) on hospital admissions for tubulointerstitial kidney diseases in each Brazilian region between 2015 and 2025, with emphasis on gender distribution. Results A total of 660,555 hospitalizations for tubulointerstitial kidney diseases were recorded nationwide. Females accounted for 67.9\% (n=448,545) and males for 32.1\% (n=212,010). By region, the Southeast had the highest number of admissions: 32.3\% (n=212,968), followed by the Northeast 25.7\% (n=169,641), South 22.4\% (n=147,911), North (11\%; n=72,608), and Center-West 8.7\% (n=57,427). Conclusion This study revealed the regional distribution of hospitalizations for tubulointerstitial kidney diseases in Brazil, highlighting a predominance in the Southeast region and among females. The higher concentration in the most populous region suggests that sociodemographic factors may influence both diagnosis and access to treatment. Moreover, the predominance of hospitalizations among women may be explained by greater healthcare-seeking behavior, a higher prevalence of autoimmune diseases, and hormonal factors that predispose to urinary tract and renal disorders.",

keywords = "Tubulointerstitial kidney diseases, Epidemiological study, Brazil",

author = "Davi Acselrad and Gabriel Parente and Marcelo Filho and Tiago Maia and Isis Holanda and Elizabeth Daher and Polianna Albuquerque and Erick Mota and Priscila Wenyan and Andre Mota and \{Silva Junior\}, Geraldo",

year = "2026",

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language = "English",

volume = "11",

pages = "1--1",

booktitle = "ISN World Congress of Nephrology (WCN) 2026 Abstracts",

publisher = "Elsevier",

address = "United Kingdom",

edition = "1",

}

Acselrad, D, Parente, G, Filho, M, Maia, T, Holanda, I, Daher, E, Albuquerque, P, Mota, E, Wenyan, P, Mota, A & Silva Junior, G 2026, WCN26-2082 EPIDEMIOLOGICAL PROFILE OF HOSPITALIZATIONS DUE TO TUBULOINTERSTITIAL KIDNEY DISEASES IN BRAZIL: ANALYSIS BY GENDER AND REGION (2015–2025). in ISN World Congress of Nephrology (WCN) 2026 Abstracts. 1 edn, vol. 11, 105799, Elsevier, Kidney International Reports, pp. 1-1. https://doi.org/10.1016/j.ekir.2026.105799

WCN26-2082 EPIDEMIOLOGICAL PROFILE OF HOSPITALIZATIONS DUE TO TUBULOINTERSTITIAL KIDNEY DISEASES IN BRAZIL: ANALYSIS BY GENDER AND REGION (2015–2025). / Acselrad, Davi; Parente, Gabriel; Filho, Marcelo et al.
ISN World Congress of Nephrology (WCN) 2026 Abstracts. Vol. 11 1. ed. Kidney International Reports: Elsevier, 2026. p. 1-1 105799.

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper published in Proceedings › peer-review

TY - GEN

T1 - WCN26-2082 EPIDEMIOLOGICAL PROFILE OF HOSPITALIZATIONS DUE TO TUBULOINTERSTITIAL KIDNEY DISEASES IN BRAZIL: ANALYSIS BY GENDER AND REGION (2015–2025)

AU - Acselrad, Davi

AU - Parente, Gabriel

AU - Filho, Marcelo

AU - Maia, Tiago

AU - Holanda, Isis

AU - Daher, Elizabeth

AU - Albuquerque, Polianna

AU - Mota, Erick

AU - Wenyan, Priscila

AU - Mota, Andre

AU - Silva Junior, Geraldo

PY - 2026/3

Y1 - 2026/3

N2 - Introduction Tubulointerstitial kidney diseases (TKD) comprise a group of disorders with similar patterns of tubular and interstitial injury, commonly caused by excessive exposure to toxins, drugs, or infections. The main categories include acute tubular necrosis and acute or chronic tubulointerstitial nephritis, the latter accounting for about 20% of acute kidney injury (AKI) cases. This study aimed to analyze the epidemiological profile of hospitalizations for tubulointerstitial kidney diseases in Brazil from 2015 to 2025. Methods This was a cross-sectional, documentary, and quantitative study using data from the Department of Informatics of the Unified Health System (DATASUS) on hospital admissions for tubulointerstitial kidney diseases in each Brazilian region between 2015 and 2025, with emphasis on gender distribution. Results A total of 660,555 hospitalizations for tubulointerstitial kidney diseases were recorded nationwide. Females accounted for 67.9% (n=448,545) and males for 32.1% (n=212,010). By region, the Southeast had the highest number of admissions: 32.3% (n=212,968), followed by the Northeast 25.7% (n=169,641), South 22.4% (n=147,911), North (11%; n=72,608), and Center-West 8.7% (n=57,427). Conclusion This study revealed the regional distribution of hospitalizations for tubulointerstitial kidney diseases in Brazil, highlighting a predominance in the Southeast region and among females. The higher concentration in the most populous region suggests that sociodemographic factors may influence both diagnosis and access to treatment. Moreover, the predominance of hospitalizations among women may be explained by greater healthcare-seeking behavior, a higher prevalence of autoimmune diseases, and hormonal factors that predispose to urinary tract and renal disorders.

AB - Introduction Tubulointerstitial kidney diseases (TKD) comprise a group of disorders with similar patterns of tubular and interstitial injury, commonly caused by excessive exposure to toxins, drugs, or infections. The main categories include acute tubular necrosis and acute or chronic tubulointerstitial nephritis, the latter accounting for about 20% of acute kidney injury (AKI) cases. This study aimed to analyze the epidemiological profile of hospitalizations for tubulointerstitial kidney diseases in Brazil from 2015 to 2025. Methods This was a cross-sectional, documentary, and quantitative study using data from the Department of Informatics of the Unified Health System (DATASUS) on hospital admissions for tubulointerstitial kidney diseases in each Brazilian region between 2015 and 2025, with emphasis on gender distribution. Results A total of 660,555 hospitalizations for tubulointerstitial kidney diseases were recorded nationwide. Females accounted for 67.9% (n=448,545) and males for 32.1% (n=212,010). By region, the Southeast had the highest number of admissions: 32.3% (n=212,968), followed by the Northeast 25.7% (n=169,641), South 22.4% (n=147,911), North (11%; n=72,608), and Center-West 8.7% (n=57,427). Conclusion This study revealed the regional distribution of hospitalizations for tubulointerstitial kidney diseases in Brazil, highlighting a predominance in the Southeast region and among females. The higher concentration in the most populous region suggests that sociodemographic factors may influence both diagnosis and access to treatment. Moreover, the predominance of hospitalizations among women may be explained by greater healthcare-seeking behavior, a higher prevalence of autoimmune diseases, and hormonal factors that predispose to urinary tract and renal disorders.

KW - Tubulointerstitial kidney diseases

KW - Epidemiological study

KW - Brazil

U2 - 10.1016/j.ekir.2026.105799

DO - 10.1016/j.ekir.2026.105799

M3 - Conference Paper published in Proceedings

VL - 11

SP - 1

EP - 1

BT - ISN World Congress of Nephrology (WCN) 2026 Abstracts

PB - Elsevier

CY - Kidney International Reports

ER -

Acselrad D, Parente G, Filho M, Maia T, Holanda I, Daher E et al. WCN26-2082 EPIDEMIOLOGICAL PROFILE OF HOSPITALIZATIONS DUE TO TUBULOINTERSTITIAL KIDNEY DISEASES IN BRAZIL: ANALYSIS BY GENDER AND REGION (2015–2025). In ISN World Congress of Nephrology (WCN) 2026 Abstracts. 1 ed. Vol. 11. Kidney International Reports: Elsevier. 2026. p. 1-1. 105799 doi: 10.1016/j.ekir.2026.105799

WCN26-2082 EPIDEMIOLOGICAL PROFILE OF HOSPITALIZATIONS DUE TO TUBULOINTERSTITIAL KIDNEY DISEASES IN BRAZIL: ANALYSIS BY GENDER AND REGION (2015–2025)

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