Whole-Genome Sequences of Burkholderia pseudomallei isolates exhibiting decreased meropenem susceptibility

Erin P. Price; Melissa Laird Smith; Ellen E. Paxinos; Luke J. Tallon; Lisa Sadzewicz; Naomi Sengamalay; Robert W. Baird; Bart J. Currie; Derek S. Sarovich

doi:10.1128/genomeA.00053-17

Whole-Genome Sequences of Burkholderia pseudomallei isolates exhibiting decreased meropenem susceptibility

Erin P. Price, Melissa Laird Smith, Ellen E. Paxinos, Luke J. Tallon, Lisa Sadzewicz, Naomi Sengamalay, Robert W. Baird, Bart J. Currie, Derek S. Sarovich

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Abstract

We report here paired isogenic Burkholderia pseudomallei genomes obtained from three patients receiving intravenous meropenem for melioidosis treatment, with post-meropenem isolates developing decreased susceptibility. Two genomes were finished, and four were drafted to improved high-quality standard. These genomes will be used to identify meropenem resistance mechanisms in B. pseudomallei.

Original language	English
Article number	e00053-17
Pages (from-to)	1-3
Number of pages	3
Journal	Genome Announcements (genomeA)
Volume	5
Issue number	14
DOIs	https://doi.org/10.1128/genomeA.00053-17
Publication status	Published - Apr 2017

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title = "Whole-Genome Sequences of Burkholderia pseudomallei isolates exhibiting decreased meropenem susceptibility",

abstract = "We report here paired isogenic Burkholderia pseudomallei genomes obtained from three patients receiving intravenous meropenem for melioidosis treatment, with post-meropenem isolates developing decreased susceptibility. Two genomes were finished, and four were drafted to improved high-quality standard. These genomes will be used to identify meropenem resistance mechanisms in B. pseudomallei.",

author = "Price, {Erin P.} and Smith, {Melissa Laird} and Paxinos, {Ellen E.} and Tallon, {Luke J.} and Lisa Sadzewicz and Naomi Sengamalay and Baird, {Robert W.} and Currie, {Bart J.} and Sarovich, {Derek S.}",

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AU - Price, Erin P.

AU - Smith, Melissa Laird

AU - Paxinos, Ellen E.

AU - Tallon, Luke J.

AU - Sadzewicz, Lisa

AU - Sengamalay, Naomi

AU - Baird, Robert W.

AU - Currie, Bart J.

AU - Sarovich, Derek S.

PY - 2017/4

Y1 - 2017/4

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AB - We report here paired isogenic Burkholderia pseudomallei genomes obtained from three patients receiving intravenous meropenem for melioidosis treatment, with post-meropenem isolates developing decreased susceptibility. Two genomes were finished, and four were drafted to improved high-quality standard. These genomes will be used to identify meropenem resistance mechanisms in B. pseudomallei.

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U2 - 10.1128/genomeA.00053-17

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JO - Genome Announcements (genomeA)

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IS - 14

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ER -

Whole-Genome Sequences of Burkholderia pseudomallei isolates exhibiting decreased meropenem susceptibility

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