Whole-genome sequencing confirms that Burkholderia pseudomallei multilocus sequence types common to both Cambodia and Australia are due to homoplasy

Brigit De Smet, Derek Sarovich, Erin Price, Mark Mayo, Vanessa Rigas, Chum Kham, Seiha Heng, Thong Phe, Matthew Holden, Julian Parkhill, Sharon J Peacock, Brian Spratt, Jan Jacobs, Peter Vandamme, Bart Currie

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Abstract

Burkholderia pseudomallei isolates with shared multilocus sequence types (STs) have not been isolated from different continents. We identified two STs shared between Australia and Cambodia. Whole-genome analysis revealed substantial diversity within STs, correctly identified the Asian or Australian origin, and confirmed that these shared STs were due to homoplasy.
Original languageEnglish
Pages (from-to)323-326
Number of pages4
JournalJournal of Clinical Microbiology
Volume53
Issue number1
DOIs
Publication statusPublished - Jan 2015

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