Whole-genome sequencing to differentiate relapse from reinfection in community-onset bacteremic acinetobacter baumannii pneumonia

Ella M. Meumann, Nicholas M. Anstey, Bart J. Currie, Kim A. Piera, Robert Baird, Derek S. Sarovich, Joshua S. Davis

    Research output: Contribution to journalArticle

    Abstract

    Community-onset bacteremic Acinetobacter baumannii pneumonia recurred in 3 of 30 (10%) patients followed prospectively, all with ongoing hazardous alcohol intake, 3 56 months after initial pneumonia. Paired isolates underwent whole-genome sequencing. Phylogenetic analysis showed that recurrence strains were all distinct from preceding strains, indicating reinfection in susceptible individuals rather than relapse.

    Original languageEnglish
    Article number263
    Pages (from-to)1-4
    Number of pages4
    JournalOpen Forum Infectious Diseases
    Volume6
    Issue number7
    DOIs
    Publication statusPublished - Jul 2019

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